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meyer-lab / FcgR-binding

A Multivalent Binding Model for FcgRs
http://asmlab.org
MIT License
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Units scale of Bruhns data #1

Closed aarmey closed 7 years ago

aarmey commented 7 years ago

In looking through a few other papers with FcgR-IgG binding data, the affinities reported vary sometimes more than 10-fold. We should probably find a few sources of Ka values and do a more rigorous comparison of the various sources. These values are really important to the ultimate predictions.

aarmey commented 7 years ago

Alexa pointed out that Bruhns values are internally inconsistent for III-Phe, Ig2 and Ig4, so those pairs are now skipped in the fitting process as of 62c7c23531102e8fc5269c9b035d099ebea43e9d.