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mgalardini / pyseer

SEER, reimplemented in python 🐍🔮
http://pyseer.readthedocs.io
Apache License 2.0
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Logistic mixed models? #79

Open cizydorczyk opened 5 years ago

cizydorczyk commented 5 years ago

Just wondering if there are any plans to implement logistic mixed models (in addition to existing linear models) for association testing?

As the documentation mentions, using a linear model with logistic data can cause a loss of power, etc. As such, it would be great if pyseer had such a logistic mixed model implementation, as well.

Conrad

johnlees commented 5 years ago

We do plan on adding this in a future release - I wrote some prototype code to interface to such a model, but haven't had a chance to fully integrate this yet. I plan to add it before the end of the year.

sarapita commented 2 years ago

is adding logistic models still part of the plan?

johnlees commented 2 years ago

Realistically no, sorry, I don't see this being added to pyseer any time soon. I expect that pyseer will remain fairly frozen with its current set of features. You could try limix directly, which I think supports this. We may at some point in the future create a separate package with these kind of features, but that wouldn't be in the near future.