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mgijax / mammalian-phenotype-ontology

Standard terms for annotating mammalian phenotypic data
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enhanced cellular glucose import #1295

Open obophenotype-user opened 11 years ago

obophenotype-user commented 11 years ago

We currently have the term enhanced cellular glucose import (MP:0003927) defined as "improved ability of a cell to take in glucose from the environment". In practice this term seems to be used both for changes in uptake rate, which may reflect changes in ability to take in glucose, and changes in total glucose uptake, which seem to reflect demand for glucose (see J:186159 and J:189886). I'm reluctant to annotate a change in total uptake to the existing term since in both cases examples it reflects a shift in respiration in the cell. I would suggest we add a term for increased cellular glucose uptake and possibly obsolete the existing term. Thanks, Sue

Reported by: sbello

Original Ticket: obo/mammalian-phenotype-requests/1295

obophenotype-user commented 11 years ago

Glucose uptake and import are considered synonymous in GO... perhaps just change the primary term name.

Original comment by: cindyJax