Closed obophenotype-user closed 9 years ago
Original comment by: nicolevasilevsky
Added terms: MP:0020051 abnormal procollagen-proline 4-dioxygenase activity MP:0020052 MP:NEW decreased procollagen-proline 4-dioxygenase activity MP:0020053 increased procollagen-proline 4-dioxygenase activity
Original comment by: nicolevasilevsky
Proposed new hierarchy MP:0005584 abnormal enzyme/ coenzyme activity -i- abnormal procollagen-proline 4-dioxygenase activity --i-- MP:NEW decreased procollagen-proline 4-dioxygenase activity --i-- MP:NEW increased procollagen-proline 4-dioxygenase activity
defs: abnormal procollagen-proline 4-dioxygenase activity def: anomaly in the ability to catalyze the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. Source: http://enzyme.expasy.org/EC/1.14.11.2
decreased procollagen-proline 4-dioxygenase activity def: decreased ability to catalyze the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. Source: http://enzyme.expasy.org/EC/1.14.11.2
increased procollagen-proline 4-dioxygenase activity def: increased ability to catalyze the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. Source: http://enzyme.expasy.org/EC/1.14.11.2
Reported by: nicolevasilevsky
Original Ticket: obo/mammalian-phenotype-requests/1631