mgijax / mammalian-phenotype-ontology

Standard terms for annotating mammalian phenotypic data
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new terms: abnormal procollagen-proline 4-dioxygenase activity #1631

Closed obophenotype-user closed 9 years ago

obophenotype-user commented 10 years ago

Proposed new hierarchy MP:0005584 abnormal enzyme/ coenzyme activity -i- abnormal procollagen-proline 4-dioxygenase activity --i-- MP:NEW decreased procollagen-proline 4-dioxygenase activity --i-- MP:NEW increased procollagen-proline 4-dioxygenase activity

defs: abnormal procollagen-proline 4-dioxygenase activity def: anomaly in the ability to catalyze the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. Source: http://enzyme.expasy.org/EC/1.14.11.2

decreased procollagen-proline 4-dioxygenase activity def: decreased ability to catalyze the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. Source: http://enzyme.expasy.org/EC/1.14.11.2

increased procollagen-proline 4-dioxygenase activity def: increased ability to catalyze the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2. Source: http://enzyme.expasy.org/EC/1.14.11.2

Reported by: nicolevasilevsky

Original Ticket: obo/mammalian-phenotype-requests/1631

obophenotype-user commented 10 years ago

Original comment by: nicolevasilevsky

obophenotype-user commented 10 years ago

Added terms: MP:0020051 abnormal procollagen-proline 4-dioxygenase activity MP:0020052 MP:NEW decreased procollagen-proline 4-dioxygenase activity MP:0020053 increased procollagen-proline 4-dioxygenase activity

Original comment by: nicolevasilevsky