new terms: abnormal thiopurine S-methyltransferase activity

[obophenotype-user]

Proposed new hierarchy MP:0005584 abnormal enzyme/ coenzyme activity -i- abnormal thiopurine S-methyltransferase activity --i-- MP:NEW decreased thiopurine S-methyltransferase activity --i-- MP:NEW increased thiopurine S-methyltransferase activity

defs: abnormal thiopurine S-methyltransferase activity def: anomaly in the ability to catalyze the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.
Source: http://enzyme.expasy.org/EC/2.1.1.67

decreased thiopurine S-methyltransferase activity def: decreased ability to catalyze the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. Source: http://enzyme.expasy.org/EC/2.1.1.67

increased thiopurine S-methyltransferase activity def: increased ability to catalyze the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether. Source: http://enzyme.expasy.org/EC/2.1.1.67

Reported by: nicolevasilevsky

Original Ticket: obo/mammalian-phenotype-requests/1634

[obophenotype-user]

• status: open --> closed-accepted
• Group: -->

Original comment by: nicolevasilevsky

[obophenotype-user]

Added terms: MP:0020063 abnormal thiopurine S-methyltransferase activity MP:0020064 decreased thiopurine S-methyltransferase activity MP:0020065 increased thiopurine S-methyltransferase activity

Original comment by: nicolevasilevsky