In J:220801, platelets of mutant mice lack alpha-granules. Based on a web search, alpha-granules are different from dense granules. Alpha-granules are secretory granules that contain growth factors (platelets contain three types of secretory granules: alpha-granules, dense granules, and lysosomes). It looks like we have several annotations that refer to alpha-granules so there is precedence for creating this term (MP: abnormal platelet alpha-granule morphology).
In J:220801, platelets of mutant mice lack alpha-granules. Based on a web search, alpha-granules are different from dense granules. Alpha-granules are secretory granules that contain growth factors (platelets contain three types of secretory granules: alpha-granules, dense granules, and lysosomes). It looks like we have several annotations that refer to alpha-granules so there is precedence for creating this term (MP: abnormal platelet alpha-granule morphology).
Reported by: monikat
Original Ticket: obo/mammalian-phenotype-requests/2079