abnormal hippocampus stratum oriens morphology

[sbello]

The term abnormal hippocampus stratum oriens morphology (MP:0011150) and its subterms are missing definitions.

[cmungall]

also sibs, ie all layers:

        is_a MP:0000813 ! abnormal hippocampus layer morphology [DEF: "any structural anomaly of the layers of the laminar structure of the hippocampus"]
         is_a MP:0008284 ! abnormal hippocampus pyramidal cell layer
         is_a MP:0008285 ! abnormal hippocampus granule cell layer
         is_a MP:0008286 ! abnormal hippocampus molecular cell layer
         is_a MP:0011149 ! abnormal hippocampus stratum lacunosum morphology
         is_a MP:0011150 ! abnormal hippocampus stratum oriens morphology *** 
         is_a MP:0011151 ! abnormal hippocampus stratum radiatum morphology

[cmungall]

See: UBERON:0002305 ! layer of hippocampus

child terms:

• UBERON:0002313 ! hippocampus pyramidal layer [DEF: "A cytoarchitectural term denoting the layer of the hippocampus in which pyramidal cells are predominant. Its location is superficial to the Stratum oriens; it is deep to the Stratum radiatum in area CA1 and area CA2 and deep to the Stratum lucidum in area CA3 (Stephan-75) (NeuroNames)."]
• UBERON:0005367 ! hippocampus granule cell layer
• UBERON:0005368 ! hippocampus molecular layer [DEF: "A cytoarchitectural region of the hippocampus consisting of a composite of the two outermost layers of the hippocampus, the Stratum lacunosum-moleculare and the Stratum radiatum (Carpenter-83). In CA3, there is an additional layer lying above the pyramidal cell layer, the stratum lucidum, which is also included here."]
• UBERON:0005370 ! hippocampus stratum lacunosum
• UBERON:0005371 ! hippocampus stratum oriens [DEF: "Layer that is part of the CA fields of the hippocampus consisting of a narrow relatively cell free layer located deep to the pyramidal cell layer extending through areas CA1, CA2 and CA3. (adapted from Paxinos The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995)"]
• UBERON:0005372 ! hippocampus stratum radiatum [DEF: "The layer located immediately above the pyramidal cell layer in CA2 and CA1 and superficial to the stratum lucidum in CA3. Suprapyramidal region in which CA3 to CA3 associational connections and CA3 to CA1 Schaffer collateral connections are located."]
• UBERON:0007637 ! hippocampus stratum lucidum [DEF: "Layer of hippocampus area CA3 lying superficial to the pyramidal cell layer that contains mossy fiber axons projecting from the dentate gyrus. A slight thickening in this layer marks the border in some species between areas CA2 and CA3. dapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 460)"]
• UBERON:0007640 ! hippocampus stratum lacunosum moleculare [DEF: "Layer of the hippocampus lying just superficial to the stratum radiatum and bounded by the pial surface of the hippocampus. The fibers of the perforant pathway fibers from entorhinal cortex and several other brain areas terminate in this layer. Adapted from Paxinos, G. The rat central nervous system, 2nd ed, Academic Press, San Diego, 1995, pg. 460)"]

[cmungall]

Is the granule layer in any part of the hippocampal formation other than the DG?

[sbello]

Added definitions to all but MP:0008285 ! abnormal hippocampus granule cell layer MP:0011149 ! abnormal hippocampus stratum lacunosum morphology

Need to work on the definition for the granule cell layer. All the definitions I can find related to stratum lacunosum are for the stratum lacunosum-moleculare see for example http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=2456

[cmungall]

See http://www.ebi.ac.uk/ols/ontologies/uberon/terms?iri=http%3A%2F%2Fpurl.obolibrary.org%2Fobo%2FUBERON_0007640