tectorial membrane terms

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abnormal Kimura membrane morphology as a child of "abnormal tectorial membrane morphology [MP:0003149]" DEF: any structural anomaly of the thickening of the lower surface of the tectorial membrane into which the hair bundles of the outer hair cells are imbedded J:160851, J:203482, J:101691

abnormal tectorial membrane marginal band morphology DEF: any structural anomaly of the dense thickening of the lateral edge of the tectorial membrane

abnormal tectorial membrane covernet morphology DEF: any structural anomaly of the anastomosing network of large caliber fibrils that run predominantly longitudinally over the upper surface of the tectorial membrane; in mice, the covernet fibrils are continuous with the underlying striated-sheet matrix of the TM, and appear as electron-dense rods that can be a micron or more in diameter

abnormal tectorial membrane striated-sheet matrix morphology DEF: any structural anomaly of the laminated, striated-sheet matrix within which collagen fibrils of the TM are imbedded; the striated sheet matrix is formed by two types of fine-diameter collagen filaments, a light and a dark staining type that lie in parallel within the plane of each sheet and are extensively linked along their length by staggered cross bridges; it originates medially within the sulcal zone, extends to the marginal band and is particularly evident in apical regions of the cochlea, where it has a less compressed appearance J:215775

DEF SOURCES Hum Mol Genet. 2014 May 15;23(10):2551-68. doi: 10.1093/hmg/ddt646. Epub 2013 Dec 20.

Curr Opin Otolaryngol Head Neck Surg. 2008 Oct;16(5):458-64. doi: 10.1097/MOO.0b013e32830e20c4.

Thanks

Anna

mgijax / mammalian-phenotype-ontology

tectorial membrane terms #2141