new terms

[obophenotype-user]

There were several terms used in analysis of the placental phenotype of mutants that are not in the MP. Can or should terms be added for placental junctional zone, or specific terms including increased/decreased number for specific placental cell types such as spongiotrophoblast cells and glycogen cells, to be consistent with the decreased trophoblast cell number term?

(This is an abstract from Placenta 21(8): 882-888

Among the different trophoblast subtypes of the mouse placenta, the glycogen cells (GC) are one of the trophoblast subtypes that invade the decidua. they directly originate from the central part of the ectoplacental cone at embryonic day (E) 7.5. PCDH12-positive cells start to accumulate glycogen from E10.5 and the first migrating cells could be observed from this age. Unlike other placental and decidual cells, GC do not express P-cadherin, which may explain their migration properties in this organ. In the decidua, GC settle in the vicinity of the maternal vascular sinuses but do not incorporate in the endothelium. By the end of gestation (E17.5), most GC islets of the decidua enter into a lytic phase and form large lacunae. These lacunae, filled with glycogen, may provide a substantial source of energy at the end of gestation or during delivery. Our data suggest that spongiotrophoblasts and GC are two independent lineages and we bring insights into GC migration and fate.)

Randy

Reported by: rbabiuk

Original Ticket: "obo/mammalian-phenotype-requests/24":https://sourceforge.net/p/obo/mammalian-phenotype-requests/24

[obophenotype-user]

• labels: --> new term request
• assigned_to: nobody --> cynthiasmith

Original comment by: cindyJax

[obophenotype-user]

added these terms:

abnormal placenta junctional zone morphology MP:0008957 abnormal glycogen cell morphology MP:0008958 abnormal spongiotrophoblast cell morphology MP:0008959

Original comment by: cindyJax

[obophenotype-user]

• status: open --> closed-accepted

Original comment by: cindyJax