mgijax / mammalian-phenotype-ontology

Standard terms for annotating mammalian phenotypic data
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related to platelet physiology #249

Closed obophenotype-user closed 9 years ago

obophenotype-user commented 15 years ago

new child of abnormal platelet physiology [MP:0005464]

abnormal platelet dense granules
def. anomalies in the function of specialized secretory organelles located in the small, irregularly shaped anuclear cells derived from fragmentation of precursor megakaryocytes that contain adenine nucleotides (ADP and ATP), ionized calcium, histamine, serotonin, and epinephrine

syn abnormal dense bodies , abnormal delta granules

children of new vocab, abnormal platelet dense granules: current abnormalities calcium and serotonin levels and new request

abnormal ATP secretion def. anomalous concentration of the major energy source adenosine triphosphate produced by dense bodies located in platelets

new children decreased ATP secretion def. reduced concentration of the major energy source for cell function increased ATP secretion def. greater than normal concentration of the major energy source for cell function

Reported by: llw2

Original Ticket: "obo/mammalian-phenotype-requests/249":https://sourceforge.net/p/obo/mammalian-phenotype-requests/249

obophenotype-user commented 15 years ago

New terms added:

abnormal platelet dense granule physiology MP:0009446 abnormal platelet ATP level MP:0009447 decreased platelet ATP level MP:0009448 increased platelet ATP level MP:0009449

Original comment by: cindyJax

obophenotype-user commented 15 years ago

Original comment by: cindyJax