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mgijax / mammalian-phenotype-ontology

Standard terms for annotating mammalian phenotypic data
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abnormal sperm migration in female genital tract #3133

Closed anna-anagnostop closed 4 years ago

anna-anagnostop commented 4 years ago

Add new terms:

abnormal sperm migration in female genital tract (a child of abnormal cell migration MP:0003091 and abnormal sperm physiology MP:0004543) DEF: any anomaly in the ability of ejaculated sperm to migrate through the female genital tract to reach the oocyte in the oviduct; during their transit in the female tract, sperm encounter different environments with various mechanical and biochemical properties; to complete the journey, each sperm has to swim in a highly viscous medium in the cervix, avoid immunological detection in the uterus, cross the uterotubal junction, and ascend into the oviduct isthmus to ultimately reach the site of fertilization, the ampullary region of the oviduct SYN: abnormal sperm migration through the female reproductive tract SOURCE: PMID: 29353867

impaired sperm migration in female genital tract DEF: impaired ability of ejaculated sperm to migrate through the female genital tract and reach the oocyte at the site of fertilization, the ampullary region of the oviduct SYN: impaired sperm migration through the female reproductive tract

(note to self: check for annotations under abnormal sperm physiology MP:0004543 or asthenozoospermia MP:0002675)

anna-anagnostop commented 4 years ago

Added new terms:

abnormal sperm migration in female genital tract MP:0031011 impaired sperm migration in female genital tract MP:0031012