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mgijax / mammalian-phenotype-ontology

Standard terms for annotating mammalian phenotypic data
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hemophagocytosis #3206

Closed anna-anagnostop closed 4 years ago

anna-anagnostop commented 4 years ago

Add new term: hemophagocytosis ( a child of abnormal macrophage physiology MP:0002451) DEF: a pathologic process of engulfment of erythrocytes, leukocytes, platelets, and their precursors by the histiocytes, either in the bone marrow or in other parts of the reticuloendothelial system; it is a nonspecific phenotypic feature observed in several conditions including hemolytic anemia, malignant disease, infections, and hemophagocytic syndrome (also known as hemophagocytic lymphohistiocytosis, a rare hyperinflammatory syndrome caused by severe hypercytokinemia due to a highly stimulated but ineffective immune process) SOURCE: http://www.mjdrdypv.org/text.asp?2019/12/1/22/250440, HP:0012156

anna-anagnostop commented 4 years ago

Added new term: hemophagocytosis MP:0031070