The gene for the diels alderase enzyme AbyU is not present in MiBIG despite being annotated by antismash in the orginal BGC. AbyU is a cyclase enzyme vital for the production of abyssomicin. It's located between AbyK and AbyI, the antiSMASH database has annotated it on the genome of Verrucosispora maris AB-18-032 which is where the BGC was taken from (https://antismash-db.secondarymetabolites.org/output/GCF_000204155.1/index.html#r1c6)
Affected BGC: BGC0000001
The gene for the diels alderase enzyme AbyU is not present in MiBIG despite being annotated by antismash in the orginal BGC. AbyU is a cyclase enzyme vital for the production of abyssomicin. It's located between AbyK and AbyI, the antiSMASH database has annotated it on the genome of Verrucosispora maris AB-18-032 which is where the BGC was taken from (https://antismash-db.secondarymetabolites.org/output/GCF_000204155.1/index.html#r1c6)
Diels alderase reference: https://pubmed.ncbi.nlm.nih.gov/27140661/