micans / mcl

MCL, the Markov Cluster algorithm, also known as Markov Clustering, is a method and program for clustering weighted or simple networks, a.k.a. graphs.
https://micans.org/mcl
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adding proteins to existing clusters #23

Closed nohayoussef closed 8 months ago

nohayoussef commented 8 months ago

Hi, I have created clusters from blast output with a subset of proteins (all versus all blastp from ~800 genomes) that I am working with. Now I need to add more proteins (I expanded to ~2000 genomes including the original 800) to the existing clusters (plus of course add more clusters if needed) using new blast outputs. I have created 2 blast output: the ~1200 extra genomes proteins versus all the ~2000 genome proteins, as well as the ~800 original against the extra ~1200. The three blast outputs can of course be combined in one huge file and be formatted to the abc format. But my question is: can I keep adding to the original clustering file, or do I just need to start all over? Thanks for your time