dsiegele
commented
7 years ago To avoid a proliferation of terms for individual antimicrobial agents, our plan is to create terms for groups of antibiotics based on their structure and then put a CHEBI ID in the annotation extension field to identify the specific chemical that was tested. The identify of the organism being assayed would be in the strain information, but I think an identifier for the organism could also be entered in the annotation extension field.
In our annotation system, the annotation would read OMP:0006052 decreased resistance to azole; AN_EXT CHEBI:10023 voriconazole.
I can see how this system would be awkward if you aren't using the OMP annotation system. I will bring this up for discussion at our next OMP call.
2016/08/01 Diane Inglis commented on issue #149:
Hello Debby,
I am systematically browsing all the branches and want to comment on the way "OMP:0000274 ! antimicrobial agent resistance phenotype" includes a list of the types of antimicrobial agents as synonyms. For the antifungal agents, it is significant to differentiate the specific antifungal drug as there are differences in efficacy toward different fungal species or strains. Would you consider creating child terms for each drug as this format loses the antifungal-specific phenotypes that i have captured and causes difficulty if there are two phenotypes such as a strain has a "decreased resistance to voriconazole" and a "normal or increased resistance to fluconazole." The display of the phenotype would be more straightforward to identify at a glance without having to look up the synonyms,
Diane