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microbialphenotypes / OMP-ontology

This repository contains the editors's working copy of OMP and public release files.
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Explorer phenotype for filamentous bacteria/fungi #202

Open jimhu-tamu opened 7 years ago

jimhu-tamu commented 7 years ago

Journal Club today we read an eLife paper that describes a different growth phase for Streptomyces. Not sure if this is represented in OMP.

https://elifesciences.org/content/6/e21738

Here, we show interactions between Streptomyces and fungi trigger a previously unobserved mode of Streptomyces development. We term these Streptomyces cells ‘explorers’, for their ability to adopt a non-branching vegetative hyphal conformation and rapidly transverse solid surfaces.

dianeoinglis commented 7 years ago

I would be cautious about using the "explorer" term given by the author. That's interpretation, not the observable. 'Hyphal branching' should definitely be represented in OMP. Hyphal branching phenotypes are relatively common. I would call the behavior in the paper "supression of hyphal branching." A defect in this growth phase might be termed "decreased/increased/abolished suppression of hyphal branching.' As an aside, Aspergillus and other fungal hyperbranching mutants are selected for higher secretion as growing tips are the highest in secretion. Fewer tips results in less overall secretion.