search

microsoft / foldingdiff

Diffusion models of protein structure; trigonometry and attention are all you need!
https://www.nature.com/articles/s41467-024-45051-2
MIT License
518 stars 57 forks source link

The input of the model do not include amino acid residues sequence infomation? #5

Closed Benstime closed 2 years ago

Benstime commented 2 years ago

so what can the model be used for?

wukevin commented 2 years ago

Correct, the model does not take amino acid sequences as input. The model is for creating (or ``hallucinating'', if you will) a new backbone structure that specifies a protein shape, starting from noise. This shape can be then engineered using tools such as ESM-IF1.