As described in Zulkower, Valentin, et al. "Robust reconstruction of gene expression profiles from reporter gene data using linear inversion." Bioinformatics 31.12 (2015): i71-i79., there is a way to calculate cellular growth rate using regularization that performs better at low cell densities than the conventional approach
As described in Zulkower, Valentin, et al. "Robust reconstruction of gene expression profiles from reporter gene data using linear inversion." Bioinformatics 31.12 (2015): i71-i79., there is a way to calculate cellular growth rate using regularization that performs better at low cell densities than the conventional approach