Closed cannin closed 2 years ago
sajo25
commented
2 years ago I'm experiencing some trouble with this. I think it's important to also collect the stderr output because some results (eg. from the function localNullModel) are displayed there. However, when I use sink(..., type="message") I get the warning "galaxy.model WARNING Datatype class not found for extension 'text'".
cannin
commented
2 years ago Can you try this to redirect stderr to stdout? https://stackoverflow.com/questions/25306819/send-r-diagnostic-messages-to-stdout-instead-stderr
sajo25
commented
2 years ago @cannin Thank you for the pointer, it works now.
I'm actually not sure anymore whether it makes sense to include all the stderr output in the file because, if the local and global null model iterations are set to higher numbers, the file would be unreasonably big. Also, I realized the local and global null model results are stored in specific variables, and can be extracted and saved in a different way. I've included the Metadata.txt file content below; please let me know which parts are useful and should be included in the final version.
R code commit:
sink("metadata.txt")
sink(stdout(), type="message")
[...]
sink(NULL)Metadata.txt content:
Loading network of 9264 nodes and 157780 interactions
Treated as undirected network
Removing multiple interactions and loops
Returning network of 9264 nodes and 68111 interactions
274 / 517 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 892 neighbor nodes in the network
For p-value 0.05 cut-off, 6 nodes were included as linker nodes
Connecting 274 candidate nodes and 6 linker nodes
Remove 208 isolated candidate nodes from the input
Final network contains 72 nodes and 152 interactions
Detecting modules using "edge betweeness" method
$netboxGraph
IGRAPH c4fc92d UN-- 72 152 --
+ attr: name (v/c), nodeType (v/c), V2 (e/c), V4 (e/c)
+ edges from c4fc92d (vertex names):
[1] CBL --PIK3R1 ADAM12--PIK3R1 CBL --PTPN11 PIK3R1--PTPN11 CBL --KIT
[6] PIK3R1--KIT PTPN11--KIT KIT --MPDZ CBL --KDR PIK3R1--KDR
[11] PTPN11--KDR TBP --RB1 PIK3R1--RB1 TBP --TAF1 RB1 --TAF1
[16] PIK3R1--ERBB2 PTPN11--ERBB2 CBL --SPRY2 PTPN11--SPRY2 CBL --FRS2
[21] PIK3R1--FRS2 PTPN11--FRS2 KDR --FRS2 RB1 --CDK6 CDK6 --CDKN2A
[26] PIK3R1--TEK PTPN11--TEK PIK3R1--GAB1 PTPN11--GAB1 KIT --GAB1
[31] KDR --GAB1 FRS2 --GAB1 CBL --PDGFRA PIK3R1--PDGFRA PTPN11--PDGFRA
[36] CBL --IFNG PTPN11--IFNG PDGFRA--IFNG TBP --TP53 TP53 --HSPA1A
+ ... omitted several edges
$netboxCommunity
IGRAPH clustering edge betweenness, groups: 10, mod: 0.52
+ groups:
$`1`
[1] "CBL" "ADAM12" "PIK3R1" "PTPN11" "KIT" "MPDZ" "KDR"
[8] "ERBB2" "SPRY2" "FRS2" "TEK" "GAB1" "PDGFRA" "IFNG"
[15] "VLDLR" "DOCK1" "EGFR" "JAK2" "CRK" "PIK3C2B" "PTPRB"
[22] "PTEN" "SH3GL2" "FGF23" "MAPK11" "PIK3CA" "HLA-DRA" "AVIL"
[29] "AGAP2"
$`2`
[1] "TBP" "RB1" "TAF1" "CDK6" "CDKN2A" "TP53" "HSPA1A" "RBBP5"
[9] "SNAPC3" "MDM4" "MDM2" "KLF6" "CDKN2C" "CDK4" "PIM1" "BNC2"
+ ... omitted several groups/vertices
$netboxOutput
geneA interaction geneB
1 CBL PP PIK3R1
2 ADAM12 PP PIK3R1
3 CBL PP PTPN11
4 PIK3R1 PP PTPN11
5 CBL PP KIT
6 PIK3R1 PP KIT
7 PTPN11 PP KIT
8 KIT PP MPDZ
9 CBL PP KDR
10 PIK3R1 STATE_CHANGE KDR
11 PTPN11 PP KDR
12 TBP PP RB1
13 PIK3R1 PP RB1
14 TBP PP TAF1
15 RB1 PP TAF1
16 PIK3R1 PP ERBB2
17 PTPN11 PP ERBB2
18 CBL PP SPRY2
19 PTPN11 PP SPRY2
20 CBL PP FRS2
21 PIK3R1 STATE_CHANGE FRS2
22 PTPN11 PP FRS2
23 KDR PP FRS2
24 RB1 PP CDK6
25 CDK6 PP CDKN2A
26 PIK3R1 PP TEK
27 PTPN11 PP TEK
28 PIK3R1 PP GAB1
29 PTPN11 PP GAB1
30 KIT STATE_CHANGE GAB1
31 KDR STATE_CHANGE GAB1
32 FRS2 PP GAB1
33 CBL PP PDGFRA
34 PIK3R1 PP PDGFRA
35 PTPN11 PP PDGFRA
36 CBL STATE_CHANGE IFNG
37 PTPN11 STATE_CHANGE IFNG
38 PDGFRA INTERACTS_WITH IFNG
39 TBP PP TP53
40 TP53 PP HSPA1A
41 PIK3R1 IN_SAME_COMPONENT VLDLR
42 CBL CO_CONTROL_INDEPENDENT_SIMILAR DOCK1
43 PIK3R1 CO_CONTROL_INDEPENDENT_SIMILAR DOCK1
44 RB1 PP RBBP5
45 TBP IN_SAME_COMPONENT SNAPC3
46 RB1 PP SNAPC3
47 RB1 PP MDM4
48 TP53 PP MDM4
49 TBP PP MDM2
50 RB1 PP MDM2
51 TAF1 PP MDM2
52 CDKN2A PP MDM2
53 TP53 PP MDM2
54 MDM4 PP MDM2
55 CBL PP EGFR
56 PIK3R1 PP EGFR
57 PTPN11 PP EGFR
58 ERBB2 PP EGFR
59 GAB1 PP EGFR
60 IFNG CO_CONTROL_INDEPENDENT_ANTI EGFR
61 CBL STATE_CHANGE JAK2
62 PIK3R1 PP JAK2
63 PTPN11 PP JAK2
64 KIT PP JAK2
65 ERBB2 PP JAK2
66 GAB1 STATE_CHANGE JAK2
67 IFNG IN_SAME_COMPONENT JAK2
68 EGFR PP JAK2
69 CBL PP CRK
70 PIK3R1 PP CRK
71 KIT PP CRK
72 KDR PP CRK
73 FRS2 PP CRK
74 TEK STATE_CHANGE CRK
75 GAB1 PP CRK
76 PDGFRA PP CRK
77 DOCK1 PP CRK
78 EGFR PP CRK
79 TP53 PP KLF6
80 KCNA5 PP PTPRE
81 PTPRD PP PTPRE
82 ERBB2 PP PIK3C2B
83 EGFR PP PIK3C2B
84 TEK PP PTPRB
85 PIK3R1 CO_CONTROL_INDEPENDENT_ANTI PTEN
86 GAB1 CO_CONTROL_INDEPENDENT_SIMILAR PTEN
87 TP53 PP PTEN
88 CBL IN_SAME_COMPONENT SH3GL2
89 EGFR IN_SAME_COMPONENT SH3GL2
90 CBL STATE_CHANGE FGF23
91 CDK6 PP CDKN2C
92 CDKN2A PP CDKN2C
93 TP53 PP CDKN2C
94 CNTN2 IN_SAME_COMPONENT NCAM1
95 RB1 PP CDK4
96 CDK6 IN_SAME_COMPONENT CDK4
97 CDKN2A PP CDK4
98 CDKN2C PP CDK4
99 NUP50 STATE_CHANGE THOC4
100 PIK3R1 STATE_CHANGE MAPK11
101 KDR STATE_CHANGE MAPK11
102 NUP50 IN_SAME_COMPONENT NUP107
103 THOC4 STATE_CHANGE NUP107
104 DCTN2 IN_SAME_COMPONENT TUBGCP2
105 PIK3R1 PP IFNAR1
106 PTPN11 PP IFNAR1
107 IFNW1 PP IFNAR1
108 IFNA2 PP IFNAR1
109 IFNB1 PP IFNAR1
110 IFNG METABOLIC_CATALYSIS IFNAR1
111 PTPN11 METABOLIC_CATALYSIS A2M
112 RB1 PP BNC2
113 TP53 PP EPHA3
114 CRK PP EPHA3
115 PIM1 PP EPHA3
116 RB1 PP CCND2
117 CDK6 PP CCND2
118 CDK4 PP CCND2
119 CDK4 PP CDKN2B
120 PPARA PP STAC3
121 IFNAR1 PP IFNA1
122 CBL CO_CONTROL_INDEPENDENT_SIMILAR PIK3CA
123 PIK3R1 PP PIK3CA
124 PTPN11 IN_SAME_COMPONENT PIK3CA
125 KDR STATE_CHANGE PIK3CA
126 FRS2 STATE_CHANGE PIK3CA
127 TEK STATE_CHANGE PIK3CA
128 GAB1 IN_SAME_COMPONENT PIK3CA
129 VLDLR IN_SAME_COMPONENT PIK3CA
130 DOCK1 CO_CONTROL_INDEPENDENT_SIMILAR PIK3CA
131 EGFR IN_SAME_COMPONENT PIK3CA
132 JAK2 CO_CONTROL_INDEPENDENT_SIMILAR PIK3CA
133 CRK CO_CONTROL_INDEPENDENT_SIMILAR PIK3CA
134 PTEN CO_CONTROL_INDEPENDENT_ANTI PIK3CA
135 MAPK11 STATE_CHANGE PIK3CA
136 A2M PP LYZ
137 CBL IN_SAME_COMPONENT HLA-DRA
138 PTPN11 STATE_CHANGE HLA-DRA
139 IFNG METABOLIC_CATALYSIS HLA-DRA
140 JAK2 CO_CONTROL_INDEPENDENT_SIMILAR HLA-DRA
141 CRK PP AVIL
142 CCT2 IN_SAME_COMPONENT CCT6A
143 DCTN2 IN_SAME_COMPONENT FGFR1OP
144 TUBGCP2 IN_SAME_COMPONENT FGFR1OP
145 NUP50 STATE_CHANGE SNRPE
146 THOC4 IN_SAME_COMPONENT SNRPE
147 NUP107 STATE_CHANGE SNRPE
148 DCTN2 IN_SAME_COMPONENT TUBGCP6
149 TUBGCP2 IN_SAME_COMPONENT TUBGCP6
150 FGFR1OP IN_SAME_COMPONENT TUBGCP6
151 PIK3R1 IN_SAME_COMPONENT AGAP2
152 PIK3CA IN_SAME_COMPONENT AGAP2
$nodeType
name type
1 CDKN2B candidate
2 EGFR candidate
3 CDKN2A candidate
4 MTAP candidate
5 PTEN candidate
6 TP53 candidate
7 SEC61G candidate
8 IFNA1 candidate
9 ELAVL2 candidate
10 IFNA8 candidate
11 IFNA2 candidate
12 KLHL9 candidate
13 IFNA5 candidate
14 CYP27B1 candidate
15 IFNW1 candidate
16 CDK4 candidate
17 AGAP2 candidate
18 METTL1 candidate
19 AVIL candidate
20 MLLT3 candidate
21 IFNB1 candidate
22 CTDSP2 candidate
23 HLA-DRA candidate
24 NF1 candidate
25 XRCC6BP1 candidate
26 MDM2 candidate
27 OS9 candidate
28 PDGFRA candidate
29 CHIC2 candidate
30 NME7 candidate
31 RB1 candidate
32 C9orf82 candidate
33 MARS candidate
34 DTX3 candidate
35 PLAA candidate
36 CPM candidate
37 MBD6 candidate
38 KIT candidate
39 TEK candidate
40 DDIT3 candidate
41 KIF5A candidate
42 MOBKL2B candidate
43 NUP107 candidate
44 DCTN2 candidate
45 PTPRD candidate
46 PAOX candidate
47 ERBB2 candidate
48 PIK3R1 candidate
49 GLI1 candidate
50 CPSF6 candidate
51 ARHGAP9 candidate
52 PIK3CA candidate
53 FRS2 candidate
54 LYZ candidate
55 INHBC candidate
56 INHBE candidate
57 YEATS4 candidate
58 LNX1 candidate
59 MDM4 candidate
60 ECHS1 candidate
61 KDR candidate
62 KISS1 candidate
63 RAB3IP candidate
64 CCT2 candidate
65 ETNK2 candidate
66 REN candidate
67 PPP1R15B candidate
68 SOX13 candidate
69 PIK3C2B candidate
70 HMGA2 candidate
71 TYRP1 candidate
72 TPD52L3 candidate
73 DOCK1 candidate
74 LAX1 candidate
75 PRELP candidate
76 SNRPE candidate
77 CCT6A candidate
78 GRIP1 candidate
79 RAP1B candidate
80 ATP2B4 candidate
81 PTPRE candidate
82 ZC3H11A candidate
83 OPTC candidate
84 ADAM12 candidate
85 FIP1L1 candidate
86 NFASC candidate
87 MKI67 candidate
88 R3HDM2 candidate
89 PSIP1 candidate
90 CNOT2 candidate
91 AVPR1A candidate
92 KIAA2026 candidate
93 CD274 candidate
94 RASL11B candidate
95 CCND2 candidate
96 BNIP3 candidate
97 GLDC candidate
98 EPHA3 candidate
99 KCNV2 candidate
100 MGMT candidate
101 STAC3 candidate
102 SNAPC3 candidate
103 HELB candidate
104 JAK2 candidate
105 GLIS3 candidate
106 CAND1 candidate
107 SGCB candidate
108 CDC37L1 candidate
109 BNC2 candidate
110 PPP2R2D candidate
111 SRGAP1 candidate
112 LMO7 candidate
113 FMOD candidate
114 ZDHHC21 candidate
115 KLRC3 candidate
116 SUMF2 candidate
117 RFX3 candidate
118 KIAA0020 candidate
119 NFIB candidate
120 RLN2 candidate
121 SH3GL2 candidate
122 IL33 candidate
123 MPDZ candidate
124 INPP5A candidate
125 VLDLR candidate
126 SLC1A1 candidate
127 DPYSL4 candidate
128 CLOCK candidate
129 CER1 candidate
130 SMARCA2 candidate
131 DST candidate
132 PHKG1 candidate
133 UHRF2 candidate
134 IRAK3 candidate
135 MYO3A candidate
136 CELSR1 candidate
137 C22orf9 candidate
138 GAD2 candidate
139 PANX2 candidate
140 RIBC2 candidate
141 TSPO candidate
142 SLC12A6 candidate
143 TMEM19 candidate
144 RAPGEF3 candidate
145 SMC1B candidate
146 BIK candidate
147 PARVG candidate
148 ARID2 candidate
149 TAF1 candidate
150 CRELD2 candidate
151 CDKN2C candidate
152 DACH1 candidate
153 KCNQ1 candidate
154 EDNRB candidate
155 SLC6A12 candidate
156 RAD51AP1 candidate
157 SBF1 candidate
158 ENO1 candidate
159 DIAPH3 candidate
160 CCR6 candidate
161 UCHL3 candidate
162 PARP11 candidate
163 TBC1D4 candidate
164 BTG2 candidate
165 NUP50 candidate
166 HDAC10 candidate
167 RPS6 candidate
168 CACNA1C candidate
169 BRD1 candidate
170 RBBP5 candidate
171 EFCAB4B candidate
172 NMU candidate
173 WIF1 candidate
174 NDUFA9 candidate
175 NTF3 candidate
176 TBK1 candidate
177 PHACTR3 candidate
178 NDFIP2 candidate
179 FGF6 candidate
180 RASSF4 candidate
181 KLF5 candidate
182 PFKP candidate
183 TUBGCP2 candidate
184 UPK3A candidate
185 KCNA1 candidate
186 ARHGAP8 candidate
187 RRAGA candidate
188 RERE candidate
189 PIM1 candidate
190 HSPA1A candidate
191 CTNNA3 candidate
192 PIM3 candidate
193 PHF10 candidate
194 HDAC7 candidate
195 APBB1IP candidate
196 KLF12 candidate
197 PTPRR candidate
198 IFNG candidate
199 GTPBP4 candidate
200 FGF23 candidate
201 PRMT8 candidate
202 TYMP candidate
203 SPRY2 candidate
204 MAPK8IP2 candidate
205 C13orf34 candidate
206 DYRK2 candidate
207 MAPK12 candidate
208 WDR37 candidate
209 MLC1 candidate
210 PDCL2 candidate
211 PDCD2 candidate
212 XPOT candidate
213 EXOC1 candidate
214 AKR1C3 candidate
215 SAPS2 candidate
216 VDR candidate
217 CNTN2 candidate
218 NDUFA4L2 candidate
219 AKR1C4 candidate
220 BCL11A candidate
221 KLHL1 candidate
222 SCEL candidate
223 ADORA1 candidate
224 SPAG6 candidate
225 MYCBP2 candidate
226 A2M candidate
227 OMG candidate
228 PLXNB2 candidate
229 PSMB1 candidate
230 RAB11FIP4 candidate
231 ATXN10 candidate
232 PCDH17 candidate
233 FBLN1 candidate
234 ARSA candidate
235 PARVB candidate
236 KLF6 candidate
237 COMMD6 candidate
238 PTPRB candidate
239 TBP candidate
240 DNAJC1 candidate
241 MYBPH candidate
242 KCNA5 candidate
243 FGFR1OP candidate
244 RPS6KA2 candidate
245 FAM120B candidate
246 CPT1B candidate
247 THOC4 candidate
248 C10orf10 candidate
249 PDE10A candidate
250 NCAM1 candidate
251 COMMD3 candidate
252 ZMYND11 candidate
253 FAF1 candidate
254 CA6 candidate
255 TUBGCP6 candidate
256 TCP10 candidate
257 THBS2 candidate
258 PPARA candidate
259 IL22 candidate
260 DIS3 candidate
261 MAPK11 candidate
262 ST7 candidate
263 DLL1 candidate
264 BRP44L candidate
265 BMI1 candidate
266 CTRB1 candidate
267 AKAP3 candidate
268 SCUBE1 candidate
269 PTPRZ1 candidate
270 SAMM50 candidate
271 WNT7B candidate
272 LEMD3 candidate
273 POU4F1 candidate
274 RABL2B candidate
275 CRK linker
276 IFNAR1 linker
277 CBL linker
278 GAB1 linker
279 CDK6 linker
280 PTPN11 linker
$moduleMembership
geneSymbol membership
CBL CBL 1
ADAM12 ADAM12 1
PIK3R1 PIK3R1 1
PTPN11 PTPN11 1
KIT KIT 1
MPDZ MPDZ 1
KDR KDR 1
ERBB2 ERBB2 1
SPRY2 SPRY2 1
FRS2 FRS2 1
TEK TEK 1
GAB1 GAB1 1
PDGFRA PDGFRA 1
IFNG IFNG 1
VLDLR VLDLR 1
DOCK1 DOCK1 1
EGFR EGFR 1
JAK2 JAK2 1
CRK CRK 1
PIK3C2B PIK3C2B 1
PTPRB PTPRB 1
PTEN PTEN 1
SH3GL2 SH3GL2 1
FGF23 FGF23 1
MAPK11 MAPK11 1
PIK3CA PIK3CA 1
HLA-DRA HLA-DRA 1
AVIL AVIL 1
AGAP2 AGAP2 1
TBP TBP 2
RB1 RB1 2
TAF1 TAF1 2
CDK6 CDK6 2
CDKN2A CDKN2A 2
TP53 TP53 2
HSPA1A HSPA1A 2
RBBP5 RBBP5 2
SNAPC3 SNAPC3 2
MDM4 MDM4 2
MDM2 MDM2 2
KLF6 KLF6 2
CDKN2C CDKN2C 2
CDK4 CDK4 2
PIM1 PIM1 2
BNC2 BNC2 2
EPHA3 EPHA3 2
CCND2 CCND2 2
CDKN2B CDKN2B 2
IFNW1 IFNW1 3
IFNA2 IFNA2 3
IFNB1 IFNB1 3
IFNAR1 IFNAR1 3
IFNA1 IFNA1 3
KCNA5 KCNA5 4
PTPRD PTPRD 4
PTPRE PTPRE 4
CNTN2 CNTN2 5
NCAM1 NCAM1 5
NUP50 NUP50 6
THOC4 THOC4 6
NUP107 NUP107 6
SNRPE SNRPE 6
DCTN2 DCTN2 7
TUBGCP2 TUBGCP2 7
FGFR1OP FGFR1OP 7
TUBGCP6 TUBGCP6 7
A2M A2M 8
LYZ LYZ 8
PPARA PPARA 9
STAC3 STAC3 9
CCT2 CCT2 10
CCT6A CCT6A 10
$neighborData
idx name localDegree globalDegree pValueRaw oddsRatio
CRK 1712 CRK 11 81 2.392088e-05 1.708732183
IFNAR1 4546 IFNAR1 6 23 4.185496e-05 2.518725729
CBL 20 CBL 14 140 6.505470e-05 1.361056889
GAB1 500 GAB1 8 57 2.483197e-04 1.751121969
CDK6 414 CDK6 5 21 3.008515e-04 2.406906108
PTPN11 84 PTPN11 14 163 3.287776e-04 1.191404667
NRCAM 883 NRCAM 3 6 4.790554e-04 3.499572228
EGF 1589 EGF 8 67 7.596036e-04 1.565999257
E4F1 723 E4F1 3 7 8.200262e-04 3.248146522
UBE2A 2002 UBE2A 3 7 8.200262e-04 3.248146522
CCNG1 2011 CCNG1 3 7 8.200262e-04 3.248146522
SH3BGRL3 9028 SH3BGRL3 2 2 8.716919e-04 5.105667426
IFNAR2 1075 IFNAR2 6 39 9.092195e-04 1.867596453
CCND1 3417 CCND1 7 55 1.104056e-03 1.642734213
SOS1 152 SOS1 10 109 1.406778e-03 1.266171170
YES1 5758 YES1 5 30 1.694793e-03 1.970584636
FES 475 FES 5 30 1.694793e-03 1.970584636
IL1B 6824 IL1B 5 30 1.694793e-03 1.970584636
EPB41L1 1514 EPB41L1 4 19 2.042576e-03 2.265163488
CRKL 95 CRKL 7 62 2.244975e-03 1.507131861
MAP2K3 2777 MAP2K3 5 32 2.282280e-03 1.894853969
GRB2 188 GRB2 16 245 2.484994e-03 0.890626990
GRB7 4 GRB7 4 20 2.494507e-03 2.202531704
NUMA1 6547 NUMA1 4 20 2.494507e-03 2.202531704
ERRFI1 13 ERRFI1 2 3 2.563877e-03 4.006943896
TRIAP1 6366 TRIAP1 2 3 2.563877e-03 4.006943896
TIE1 485 TIE1 2 3 2.563877e-03 4.006943896
KCNE4 1027 KCNE4 2 3 2.563877e-03 4.006943896
CELSR2 6197 CELSR2 2 3 2.563877e-03 4.006943896
PDGFRB 469 PDGFRB 7 67 3.503258e-03 1.420311763
SHB 30 SHB 4 23 4.252370e-03 2.035143264
RAP1A 5820 RAP1A 6 54 4.974753e-03 1.495902022
IL1R1 5794 IL1R1 4 24 4.985976e-03 1.985021367
BTC 5506 BTC 2 4 5.027605e-03 3.496007019
ZNHIT1 4450 ZNHIT1 2 4 5.027605e-03 3.496007019
NQO1 5888 NQO1 2 4 5.027605e-03 3.496007019
PTPRO 92 PTPRO 2 4 5.027605e-03 3.496007019
ECM1 6017 ECM1 2 4 5.027605e-03 3.496007019
SH3KBP1 302 SH3KBP1 5 39 5.515940e-03 1.667299356
RAD54B 1259 RAD54B 3 13 5.872802e-03 2.400180733
PIK3R2 7 PIK3R2 5 40 6.154853e-03 1.638614320
STAT5B 890 STAT5B 5 40 6.154853e-03 1.638614320
PTK2 109 PTK2 9 113 6.202610e-03 1.112722170
SOCS1 44 SOCS1 6 57 6.494537e-03 1.435548460
ITGB4 1663 ITGB4 5 41 6.844053e-03 1.610723080
ANGPT2 2718 ANGPT2 3 14 7.312806e-03 2.309097590
TEC 32 TEC 4 27 7.683067e-03 1.848111328
PIK3C2A 9027 PIK3C2A 2 5 8.216083e-03 3.159423517
SERTAD1 2681 SERTAD1 2 5 8.216083e-03 3.159423517
MAGEB18 5515 MAGEB18 2 5 8.216083e-03 3.159423517
MTSS1 5889 MTSS1 2 5 8.216083e-03 3.159423517
GTPBP3 5669 GTPBP3 2 5 8.216083e-03 3.159423517
PIK3CB 497 PIK3CB 3 15 8.943592e-03 2.225604604
SNX6 662 SNX6 3 15 8.943592e-03 2.225604604
PHB 4988 PHB 3 15 8.943592e-03 2.225604604
VAV2 49 VAV2 4 29 9.929120e-03 1.766210232
VEGFA 141 VEGFA 6 63 1.050255e-02 1.324673879
SMARCB1 1309 SMARCB1 3 16 1.077013e-02 2.148532173
NFYB 1750 NFYB 3 16 1.077013e-02 2.148532173
SERPINA3 5760 SERPINA3 3 16 1.077013e-02 2.148532173
KLF4 1764 KLF4 2 6 1.208460e-02 2.907997811
MNDA 5912 MNDA 2 6 1.208460e-02 2.907997811
EID1 1335 EID1 2 6 1.208460e-02 2.907997811
CREG1 1340 CREG1 2 6 1.208460e-02 2.907997811
SERPINB2 6427 SERPINB2 2 6 1.208460e-02 2.907997811
CNTNAP1 342 CNTNAP1 2 6 1.208460e-02 2.907997811
CNOT3 8133 CNOT3 2 6 1.208460e-02 2.907997811
IFNGR2 578 IFNGR2 2 6 1.208460e-02 2.907997811
GRB14 631 GRB14 3 17 1.279644e-02 2.076961807
MSX1 5047 MSX1 3 17 1.279644e-02 2.076961807
EHMT2 5521 EHMT2 3 17 1.279644e-02 2.076961807
L1CAM 745 L1CAM 3 17 1.279644e-02 2.076961807
STAT5A 984 STAT5A 6 67 1.399419e-02 1.256973774
HDAC3 243 HDAC3 6 67 1.399419e-02 1.256973774
CDKN1A 4200 CDKN1A 6 67 1.399419e-02 1.256973774
E2F1 760 E2F1 7 87 1.431889e-02 1.132455790
DLG1 1467 DLG1 6 68 1.497986e-02 1.240732391
CBLB 47 CBLB 4 33 1.560405e-02 1.620052142
GRB10 93 GRB10 4 33 1.560405e-02 1.620052142
CBLC 185 CBLC 2 7 1.659043e-02 2.707215825
SCAMP1 3798 SCAMP1 2 7 1.659043e-02 2.707215825
KRT7 6613 KRT7 2 7 1.659043e-02 2.707215825
SOCS5 7772 SOCS5 2 7 1.659043e-02 2.707215825
PGF 144 PGF 2 7 1.659043e-02 2.707215825
RND1 3238 RND1 2 7 1.659043e-02 2.707215825
NAGK 887 NAGK 2 7 1.659043e-02 2.707215825
CNOT8 3472 CNOT8 2 7 1.659043e-02 2.707215825
NCAN 1707 NCAN 2 7 1.659043e-02 2.707215825
HSP90AA1 771 HSP90AA1 11 179 1.718107e-02 0.826361798
IL23A 3473 IL23A 4 34 1.728386e-02 1.586604121
IL23R 3474 IL23R 4 34 1.728386e-02 1.586604121
MAPKAPK5 247 MAPKAPK5 3 19 1.745994e-02 1.947527235
FGFR2 273 FGFR2 3 19 1.745994e-02 1.947527235
HMGB1 5307 HMGB1 5 52 1.826877e-02 1.346076373
GFRA1 3075 GFRA1 4 35 1.907234e-02 1.554231645
GDNF 7287 GDNF 4 35 1.907234e-02 1.554231645
PTPRS 903 PTPRS 3 20 2.010089e-02 1.888575295
BAG1 630 BAG1 3 20 2.010089e-02 1.888575295
ITCH 1942 ITCH 3 20 2.010089e-02 1.888575295
HCFC1 199 HCFC1 3 20 2.010089e-02 1.888575295
PPP1CA 846 PPP1CA 6 73 2.063642e-02 1.163211157
HUWE1 6569 HUWE1 2 8 2.169276e-02 2.540050437
ZCCHC10 8566 ZCCHC10 2 8 2.169276e-02 2.540050437
CSF2RA 480 CSF2RA 2 8 2.169276e-02 2.540050437
DUSP16 2781 DUSP16 2 8 2.169276e-02 2.540050437
STAT3 3499 STAT3 9 139 2.203355e-02 0.887605775
NGF 7420 NGF 5 55 2.277761e-02 1.284497234
CD82 12 CD82 3 21 2.294927e-02 1.832893993
PTPN2 636 PTPN2 3 21 2.294927e-02 1.832893993
BDNF 5052 BDNF 3 21 2.294927e-02 1.832893993
CDC37 2552 CDC37 3 21 2.294927e-02 1.832893993
FYN 2268 FYN 11 187 2.295394e-02 0.779069436
MET 1459 MET 5 56 2.442689e-02 1.264776899
SP3 1310 SP3 4 38 2.510654e-02 1.462924952
HSP90AB1 2031 HSP90AB1 3 22 2.600516e-02 1.780138795
TBX21 7775 TBX21 3 22 2.600516e-02 1.780138795
RAPGEF1 1851 RAPGEF1 3 22 2.600516e-02 1.780138795
NT5C2 5380 NT5C2 3 22 2.600516e-02 1.780138795
SNAPC1 3720 SNAPC1 3 22 2.600516e-02 1.780138795
HIF1A 228 HIF1A 7 99 2.713980e-02 0.992156621
CCND3 4708 CCND3 4 39 2.734546e-02 1.434239917
FGFR1 1619 FGFR1 4 39 2.734546e-02 1.434239917
SNX4 638 SNX4 2 9 2.735265e-02 2.396838278
CR2 3631 CR2 2 9 2.735265e-02 2.396838278
CBX8 3635 CBX8 2 9 2.735265e-02 2.396838278
PDGFA 6798 PDGFA 2 9 2.735265e-02 2.396838278
ELF1 68 ELF1 2 9 2.735265e-02 2.396838278
TUB 536 TUB 2 9 2.735265e-02 2.396838278
CSPG4 3010 CSPG4 2 9 2.735265e-02 2.396838278
SUB1 776 SUB1 2 9 2.735265e-02 2.396838278
SDC2 411 SDC2 5 58 2.795137e-02 1.226453289
SP1 67 SP1 8 122 2.807171e-02 0.905223381
FER 961 FER 3 23 2.926808e-02 1.730016898
BCL2L1 2003 BCL2L1 5 59 2.982844e-02 1.207822341
NCK2 633 NCK2 4 41 3.217088e-02 1.379208316
HIST3H3 1584 HIST3H3 4 41 3.217088e-02 1.379208316
MAP2K4 722 MAP2K4 4 41 3.217088e-02 1.379208316
TRAT1 177 TRAT1 2 10 3.353288e-02 2.271563808
PRKRA 1324 PRKRA 2 10 3.353288e-02 2.271563808
CNOT7 3471 CNOT7 2 10 3.353288e-02 2.271563808
PJA1 2348 PJA1 2 10 3.353288e-02 2.271563808
PDGFB 627 PDGFB 2 10 3.353288e-02 2.271563808
DTX1 1940 DTX1 2 10 3.353288e-02 2.271563808
ADAM10 5757 ADAM10 2 10 3.353288e-02 2.271563808
CNTN1 753 CNTN1 2 10 3.353288e-02 2.271563808
ITGB1 2968 ITGB1 7 104 3.425764e-02 0.938950806
CDH1 573 CDH1 4 42 3.475882e-02 1.352779307
ITGA6 1661 ITGA6 4 42 3.475882e-02 1.352779307
ITGA4 2970 ITGA4 4 42 3.475882e-02 1.352779307
FOS 2614 FOS 8 128 3.590807e-02 0.853472242
BRF1 2024 BRF1 3 25 3.641019e-02 1.636703485
CSF2RB 5753 CSF2RB 3 25 3.641019e-02 1.636703485
TIAM1 66 TIAM1 3 25 3.641019e-02 1.636703485
RELN 2133 RELN 3 25 3.641019e-02 1.636703485
IRF1 5938 IRF1 4 43 3.746423e-02 1.327025163
CAV1 660 CAV1 6 85 3.969455e-02 0.998235989
SOCS7 550 SOCS7 2 11 4.019798e-02 2.160226833
CAV3 1487 CAV3 2 11 4.019798e-02 2.160226833
EPS15L1 4371 EPS15L1 2 11 4.019798e-02 2.160226833
ATF3 227 ATF3 2 11 4.019798e-02 2.160226833
SPIB 233 SPIB 2 11 4.019798e-02 2.160226833
PIK3R3 509 PIK3R3 2 11 4.019798e-02 2.160226833
RING1 1311 RING1 2 11 4.019798e-02 2.160226833
MATK 90 MATK 2 11 4.019798e-02 2.160226833
TRPV1 3803 TRPV1 2 11 4.019798e-02 2.160226833
KLHL12 5699 KLHL12 2 11 4.019798e-02 2.160226833
KCNB1 1617 KCNB1 2 11 4.019798e-02 2.160226833
NOV 5203 NOV 2 11 4.019798e-02 2.160226833
ITGA2B 655 ITGA2B 3 26 4.028573e-02 1.593106859
SMO 3370 SMO 3 26 4.028573e-02 1.593106859
PFDN1 3415 PFDN1 3 26 4.028573e-02 1.593106859
MAP3K11 1168 MAP3K11 3 26 4.028573e-02 1.593106859
YWHAG 503 YWHAG 14 282 4.035649e-02 0.592298723
RELA 3410 RELA 9 155 4.040396e-02 0.770146071
MYC 847 MYC 7 109 4.252034e-02 0.888377987
STAT1 204 STAT1 7 109 4.252034e-02 0.888377987
SRC 89 SRC 12 233 4.385189e-02 0.634033027
ITGA5 5007 ITGA5 3 27 4.436106e-02 1.551322636
CCT5 1688 CCT5 3 27 4.436106e-02 1.551322636
ANGPT1 2717 ANGPT1 3 27 4.436106e-02 1.551322636
GTF2E2 1781 GTF2E2 4 46 4.628719e-02 1.253486545
SNX2 637 SNX2 2 12 4.731406e-02 2.060032022
TNC 882 TNC 2 12 4.731406e-02 2.060032022
MAGI3 884 MAGI3 2 12 4.731406e-02 2.060032022
ERH 5581 ERH 2 12 4.731406e-02 2.060032022
SH2B3 99 SH2B3 2 12 4.731406e-02 2.060032022
PFDN6 4210 PFDN6 2 12 4.731406e-02 2.060032022
PLSCR1 402 PLSCR1 5 67 4.769376e-02 1.069960830
PRKCA 87 PRKCA 10 185 4.787593e-02 0.690105058
NOS3 3215 NOS3 3 28 4.863329e-02 1.511205763
NR3C1 2352 NR3C1 6 91 5.239598e-02 0.924803083
SHC1 143 SHC1 9 163 5.265182e-02 0.716072426
EDN1 1888 EDN1 3 29 5.309915e-02 1.472627931
MAGI2 2693 MAGI2 2 13 5.484883e-02 1.968948879
CEBPE 1845 CEBPE 2 13 5.484883e-02 1.968948879
PAX5 4797 PAX5 2 13 5.484883e-02 1.968948879
TRIM23 5404 TRIM23 2 13 5.484883e-02 1.968948879
SYNGAP1 2334 SYNGAP1 2 13 5.484883e-02 1.968948879
PFDN2 4209 PFDN2 2 13 5.484883e-02 1.968948879
COMMD1 4841 COMMD1 2 13 5.484883e-02 1.968948879
CEP72 5541 CEP72 5 70 5.572757e-02 1.022741166
CHEK2 1819 CHEK2 3 30 5.775507e-02 1.435475096
EFEMP2 2023 EFEMP2 3 30 5.775507e-02 1.435475096
PPP2R1B 3491 PPP2R1B 3 30 5.775507e-02 1.435475096
SLBP 7562 SLBP 3 30 5.775507e-02 1.435475096
YWHAZ 463 YWHAZ 7 117 5.824104e-02 0.812324769
BTK 27 BTK 5 71 5.856873e-02 1.007477310
CDKN1B 412 CDKN1B 4 50 5.969339e-02 1.163091181
MAPK1 24 MAPK1 9 168 6.142492e-02 0.683656573
ERBB3 477 ERBB3 3 31 6.259714e-02 1.399645437
PAFAH1B3 3447 PAFAH1B3 3 31 6.259714e-02 1.399645437
BDP1 4989 BDP1 3 31 6.259714e-02 1.399645437
ARF6 1421 ARF6 3 31 6.259714e-02 1.399645437
PTPN6 86 PTPN6 7 119 6.266503e-02 0.794161818
STAM2 958 STAM2 2 14 6.277150e-02 1.885455893
TGFA 5750 TGFA 2 14 6.277150e-02 1.885455893
HBEGF 7070 HBEGF 2 14 6.277150e-02 1.885455893
VBP1 2169 VBP1 2 14 6.277150e-02 1.885455893
CCT8 6648 CCT8 2 14 6.277150e-02 1.885455893
RFX1 693 RFX1 2 14 6.277150e-02 1.885455893
EDF1 1371 EDF1 2 14 6.277150e-02 1.885455893
DRAP1 1779 DRAP1 2 14 6.277150e-02 1.885455893
PLCG1 21 PLCG1 7 120 6.495197e-02 0.785199558
RHOA 4909 RHOA 7 121 6.728899e-02 0.776314915
IL12RB1 2917 IL12RB1 5 74 6.758064e-02 0.963016276
IL12B 6981 IL12B 5 74 6.758064e-02 0.963016276
TP73 1074 TP73 3 32 6.762123e-02 1.365047673
IL4R 5792 IL4R 3 32 6.762123e-02 1.365047673
NEDD8 1449 NEDD8 2 15 7.105272e-02 1.808383462
CUL3 422 CUL3 2 15 7.105272e-02 1.808383462
SOCS6 3032 SOCS6 2 15 7.105272e-02 1.808383462
IRS4 498 IRS4 2 15 7.105272e-02 1.808383462
SGMS1 9257 SGMS1 2 15 7.105272e-02 1.808383462
GNA11 2813 GNA11 2 15 7.105272e-02 1.808383462
PFDN4 1971 PFDN4 2 15 7.105272e-02 1.808383462
CBX3 124 CBX3 2 15 7.105272e-02 1.808383462
IFNGR1 5756 IFNGR1 2 15 7.105272e-02 1.808383462
LEP 5910 LEP 2 15 7.105272e-02 1.808383462
DLG4 6 DLG4 6 99 7.278902e-02 0.834459247
NTRK1 531 NTRK1 3 33 7.282295e-02 1.331599651
FLT1 5746 FLT1 3 33 7.282295e-02 1.331599651
POLR3E 1706 POLR3E 3 33 7.282295e-02 1.331599651
POLR3B 7478 POLR3B 3 33 7.282295e-02 1.331599651
POLR3D 7479 POLR3D 3 33 7.282295e-02 1.331599651
POLR3H 7480 POLR3H 3 33 7.282295e-02 1.331599651
NCK1 154 NCK1 5 76 7.399310e-02 0.934421364
TUBA1A 1598 TUBA1A 5 76 7.399310e-02 0.934421364
BCL2 2255 BCL2 5 76 7.399310e-02 0.934421364
TUBG1 478 TUBG1 5 76 7.399310e-02 0.934421364
DYNLL1 516 DYNLL1 7 125 7.713840e-02 0.741526023
CSNK1D 2009 CSNK1D 5 77 7.731960e-02 0.920420125
POLR3A 3898 POLR3A 3 34 7.819770e-02 1.299227176
HSF1 5946 HSF1 3 34 7.819770e-02 1.299227176
PPIA 2535 PPIA 2 16 7.966452e-02 1.736813096
CTLA4 2979 CTLA4 2 16 7.966452e-02 1.736813096
UGCG 3097 UGCG 2 16 7.966452e-02 1.736813096
MDK 1036 MDK 2 16 7.966452e-02 1.736813096
EOMES 7700 EOMES 2 16 7.966452e-02 1.736813096
EEF2K 5881 EEF2K 2 16 7.966452e-02 1.736813096
ITGB3 624 ITGB3 5 78 8.072563e-02 0.906609142
AKAP9 920 AKAP9 5 78 8.072563e-02 0.906609142
AKT1 3414 AKT1 10 204 8.084535e-02 0.585154194
GIT1 546 GIT1 4 56 8.323070e-02 1.041059258
CD28 472 CD28 3 35 8.374070e-02 1.267863007
FGFR3 1610 FGFR3 3 35 8.374070e-02 1.267863007
CDK5RAP2 4039 CDK5RAP2 5 79 8.421064e-02 0.892983271
UBB 1650 UBB 4 57 8.753859e-02 1.022078886
HRAS 26 HRAS 6 104 8.754771e-02 0.781801990
PTN 5306 PTN 5 80 8.777401e-02 0.879537576
PTPRA 716 PTPRA 2 17 8.858026e-02 1.670010307
ELN 5793 ELN 2 17 8.858026e-02 1.670010307
PFDN5 1879 PFDN5 2 17 8.858026e-02 1.670010307
DNAJA3 897 DNAJA3 2 17 8.858026e-02 1.670010307
IL27 4535 IL27 2 17 8.858026e-02 1.670010307
MLL 4885 MLL 2 17 8.858026e-02 1.670010307
LZTS1 4724 LZTS1 3 36 8.944701e-02 1.237446019
PTK2B 35 PTK2B 5 82 9.513305e-02 0.853167930
NUP153 2414 NUP153 5 82 9.513305e-02 0.853167930
USP7 2017 USP7 3 37 9.531156e-02 1.207920483
NGFR 1698 NGFR 4 59 9.647057e-02 0.985153705
VAV3 131 VAV3 2 18 9.777459e-02 1.607378523
PDCD6IP 3247 PDCD6IP 2 18 9.777459e-02 1.607378523
EDNRA 6609 EDNRA 2 18 9.777459e-02 1.607378523
PPM1A 505 PPM1A 2 18 9.777459e-02 1.607378523
CD22 5772 CD22 2 18 9.777459e-02 1.607378523
CCT4 5855 CCT4 2 18 9.777459e-02 1.607378523
IL27RA 2915 IL27RA 2 18 9.777459e-02 1.607378523
TICAM2 2393 TICAM2 2 18 9.777459e-02 1.607378523
SIN3A 766 SIN3A 5 83 9.892720e-02 0.840235039
EWSR1 2138 EWSR1 6 108 1.004496e-01 0.741545796
RPS6KB1 1403 RPS6KB1 4 60 1.010911e-01 0.967184162
PRMT1 561 PRMT1 3 38 1.013291e-01 1.179235447
SMARCA4 764 SMARCA4 3 38 1.013291e-01 1.179235447
POLR3F 4212 POLR3F 3 38 1.013291e-01 1.179235447
NUP214 4974 NUP214 5 84 1.027967e-01 0.827464428
ABL1 130 ABL1 6 109 1.038241e-01 0.731724464
PXN 862 PXN 5 85 1.067405e-01 0.814852038
NFKBIA 4056 NFKBIA 5 85 1.067405e-01 0.814852038
EPN1 2417 EPN1 2 19 1.072234e-01 1.548426584
WRN 686 WRN 2 19 1.072234e-01 1.548426584
EGR1 4857 EGR1 2 19 1.072234e-01 1.548426584
TOP2A 6463 TOP2A 2 19 1.072234e-01 1.548426584
BMX 4722 BMX 2 19 1.072234e-01 1.548426584
ERBB2IP 9 ERBB2IP 2 19 1.072234e-01 1.548426584
DAPP1 7689 DAPP1 2 19 1.072234e-01 1.548426584
IRF3 618 IRF3 2 19 1.072234e-01 1.548426584
HLA-DRB1 1660 HLA-DRB1 3 39 1.074944e-01 1.151344207
WT1 383 WT1 3 40 1.138021e-01 1.124203847
DAB1 542 DAB1 3 40 1.138021e-01 1.124203847
IL2 6841 IL2 6 112 1.142978e-01 0.702813463
CEBPB 268 CEBPB 4 63 1.155477e-01 0.915112636
RBBP7 1319 RBBP7 4 63 1.155477e-01 0.915112636
PPP2CA 1055 PPP2CA 4 63 1.155477e-01 0.915112636
CD3E 495 CD3E 4 63 1.155477e-01 0.915112636
AZI1 7153 AZI1 4 63 1.155477e-01 0.915112636
CEP164 7182 CEP164 4 63 1.155477e-01 0.915112636
CEP290 7183 CEP290 4 63 1.155477e-01 0.915112636
CEP78 7184 CEP78 4 63 1.155477e-01 0.915112636
SDCCAG8 7546 SDCCAG8 4 63 1.155477e-01 0.915112636
TSGA14 7618 TSGA14 4 63 1.155477e-01 0.915112636
CCNA1 1327 CCNA1 2 20 1.169037e-01 1.492745281
GADD45A 4719 GADD45A 2 20 1.169037e-01 1.492745281
PTPRF 572 PTPRF 2 20 1.169037e-01 1.492745281
WWP2 643 WWP2 2 20 1.169037e-01 1.492745281
NID1 5063 NID1 2 20 1.169037e-01 1.492745281
F11R 885 F11R 2 20 1.169037e-01 1.492745281
ESR1 3236 ESR1 9 193 1.186857e-01 0.535216081
NR2F2 1728 NR2F2 3 41 1.202467e-01 1.097774838
GEMIN5 1474 GEMIN5 3 41 1.202467e-01 1.097774838
GEMIN6 3250 GEMIN6 3 41 1.202467e-01 1.097774838
IL4 7721 IL4 3 41 1.202467e-01 1.097774838
CEP135 1022 CEP135 4 64 1.205581e-01 0.898333607
ODF2 1529 ODF2 4 64 1.205581e-01 0.898333607
TUBGCP3 1992 TUBGCP3 4 64 1.205581e-01 0.898333607
CETN2 2234 CETN2 4 64 1.205581e-01 0.898333607
CEP110 4046 CEP110 4 64 1.205581e-01 0.898333607
CEP152 4274 CEP152 4 64 1.205581e-01 0.898333607
CEP192 6770 CEP192 4 64 1.205581e-01 0.898333607
CEP250 7034 CEP250 4 64 1.205581e-01 0.898333607
ALMS1 7125 ALMS1 4 64 1.205581e-01 0.898333607
SSNA1 7598 SSNA1 4 64 1.205581e-01 0.898333607
TUBGCP4 7620 TUBGCP4 4 64 1.205581e-01 0.898333607
TUBGCP5 7621 TUBGCP5 4 64 1.205581e-01 0.898333607
SFI1 2239 SFI1 4 65 1.256605e-01 0.881827809
TUBB4 3043 TUBB4 4 65 1.256605e-01 0.881827809
TUBG2 3789 TUBG2 4 65 1.256605e-01 0.881827809
NEDD1 5930 NEDD1 4 65 1.256605e-01 0.881827809
NCOR1 450 NCOR1 4 65 1.256605e-01 0.881827809
ZBTB17 1878 ZBTB17 2 21 1.267936e-01 1.439990084
ATR 147 ATR 2 21 1.267936e-01 1.439990084
ADH4 7101 ADH4 2 21 1.267936e-01 1.439990084
ADH6 7102 ADH6 2 21 1.267936e-01 1.439990084
ADH7 7103 ADH7 2 21 1.267936e-01 1.439990084
NUMB 653 NUMB 2 21 1.267936e-01 1.439990084
GTF3C2 3091 GTF3C2 2 21 1.267936e-01 1.439990084
PIK3CG 171 PIK3CG 2 21 1.267936e-01 1.439990084
JUND 2650 JUND 2 21 1.267936e-01 1.439990084
CDH5 576 CDH5 2 21 1.267936e-01 1.439990084
CCT7 1689 CCT7 2 21 1.267936e-01 1.439990084
CCT3 2174 CCT3 2 21 1.267936e-01 1.439990084
SPHK1 3591 SPHK1 2 21 1.267936e-01 1.439990084
SNAPC4 2629 SNAPC4 2 21 1.267936e-01 1.439990084
SNAPC2 2631 SNAPC2 2 21 1.267936e-01 1.439990084
ZNF143 7647 ZNF143 2 21 1.267936e-01 1.439990084
EBI3 4040 EBI3 2 21 1.267936e-01 1.439990084
ILK 651 ILK 2 21 1.267936e-01 1.439990084
KRT18 3261 KRT18 3 42 1.268227e-01 1.072020694
ATM 1262 ATM 3 42 1.268227e-01 1.072020694
GEMIN7 2806 GEMIN7 3 42 1.268227e-01 1.072020694
MMP2 4175 MMP2 3 42 1.268227e-01 1.072020694
BAD 2401 BAD 3 42 1.268227e-01 1.072020694
SMAD3 225 SMAD3 10 225 1.304227e-01 0.480235145
PCNT 1990 PCNT 4 66 1.308529e-01 0.865586426
CEP57 4623 CEP57 4 66 1.308529e-01 0.865586426
CEP63 5548 CEP63 4 66 1.308529e-01 0.865586426
OFD1 6122 OFD1 4 66 1.308529e-01 0.865586426
DYNC1I2 6177 DYNC1I2 4 66 1.308529e-01 0.865586426
DCTN3 7225 DCTN3 4 66 1.308529e-01 0.865586426
MAPK9 222 MAPK9 3 43 1.335245e-01 1.046907666
SNUPN 3815 SNUPN 3 43 1.335245e-01 1.046907666
PICK1 17 PICK1 3 43 1.335245e-01 1.046907666
CCDC90B 8446 CCDC90B 2 22 1.368724e-01 1.389868187
STK11 2016 STK11 2 22 1.368724e-01 1.389868187
TP53BP2 65 TP53BP2 2 22 1.368724e-01 1.389868187
GHR 490 GHR 2 22 1.368724e-01 1.389868187
TSHR 2402 TSHR 2 22 1.368724e-01 1.389868187
EFNB2 1249 EFNB2 2 22 1.368724e-01 1.389868187
BRF2 1350 BRF2 2 22 1.368724e-01 1.389868187
GADD45B 454 GADD45B 2 22 1.368724e-01 1.389868187
IL18RAP 3135 IL18RAP 2 22 1.368724e-01 1.389868187
UBTF 483 UBTF 3 44 1.403468e-01 1.022404475
ACTR1A 1515 ACTR1A 4 68 1.414980e-01 0.833863720
TUBB2C 1989 TUBB2C 4 68 1.414980e-01 0.833863720
DYNC1H1 7243 DYNC1H1 4 68 1.414980e-01 0.833863720
RASA1 1638 RASA1 5 94 1.454134e-01 0.707859986
PLK4 2923 PLK4 4 69 1.469460e-01 0.818366762
PRKAR1A 934 PRKAR1A 2 23 1.471205e-01 1.342128649
AP2A2 2835 AP2A2 2 23 1.471205e-01 1.342128649
AGTR1 5752 AGTR1 2 23 1.471205e-01 1.342128649
TFAP2A 5774 TFAP2A 2 23 1.471205e-01 1.342128649
ADH1A 7098 ADH1A 2 23 1.471205e-01 1.342128649
ADH1B 7099 ADH1B 2 23 1.471205e-01 1.342128649
ADH1C 7100 ADH1C 2 23 1.471205e-01 1.342128649
HSD11B1 7337 HSD11B1 2 23 1.471205e-01 1.342128649
GCKR 6695 GCKR 2 23 1.471205e-01 1.342128649
PFN1 470 PFN1 2 23 1.471205e-01 1.342128649
CTSB 344 CTSB 2 23 1.471205e-01 1.342128649
APLP1 5241 APLP1 2 23 1.471205e-01 1.342128649
RXRG 4733 RXRG 2 23 1.471205e-01 1.342128649
SAP18 3321 SAP18 3 45 1.472838e-01 0.998482076
NCOA2 1369 NCOA2 3 45 1.472838e-01 0.998482076
PLK1 819 PLK1 8 175 1.473258e-01 0.518825796
PAK1 5 PAK1 4 70 1.524744e-01 0.803102906
SMN1 1463 SMN1 4 70 1.524744e-01 0.803102906
NUP205 4673 NUP205 4 70 1.524744e-01 0.803102906
AAAS 7075 AAAS 4 70 1.524744e-01 0.803102906
NUP188 7432 NUP188 4 70 1.524744e-01 0.803102906
NUP35 7433 NUP35 4 70 1.524744e-01 0.803102906
NUPL2 7437 NUPL2 4 70 1.524744e-01 0.803102906
PRKACA 338 PRKACA 10 233 1.528480e-01 0.442872543
JUN 2615 JUN 8 177 1.540306e-01 0.506729514
STAT4 205 STAT4 3 46 1.543301e-01 0.975113451
IRS2 487 IRS2 3 46 1.543301e-01 0.975113451
KRT15 5298 KRT15 3 46 1.543301e-01 0.975113451
CDC42 4806 CDC42 5 96 1.547326e-01 0.685534919
MUC1 1694 MUC1 2 24 1.575190e-01 1.296554773
HSD3B7 7339 HSD3B7 2 24 1.575190e-01 1.296554773
NSDHL 7426 NSDHL 2 24 1.575190e-01 1.296554773
SNW1 1321 SNW1 2 24 1.575190e-01 1.296554773
PHAX 7458 PHAX 2 24 1.575190e-01 1.296554773
MST1R 56 MST1R 2 24 1.575190e-01 1.296554773
TICAM1 4263 TICAM1 2 24 1.575190e-01 1.296554773
PAICS 5317 PAICS 2 24 1.575190e-01 1.296554773
NFIC 2577 NFIC 2 24 1.575190e-01 1.296554773
IL18R1 3134 IL18R1 2 24 1.575190e-01 1.296554773
NUP155 74 NUP155 4 71 1.580807e-01 0.788065193
NUP93 7436 NUP93 4 71 1.580807e-01 0.788065193
PRKAR2B 937 PRKAR2B 4 71 1.580807e-01 0.788065193
CEP76 5675 CEP76 4 71 1.580807e-01 0.788065193
SLC9A3R1 279 SLC9A3R1 3 47 1.614801e-01 0.952273424
IL6ST 33 IL6ST 3 47 1.614801e-01 0.952273424
KRTAP4-12 5702 KRTAP4-12 4 72 1.637624e-01 0.773246969
NUP88 3200 NUP88 4 72 1.637624e-01 0.773246969
CENPJ 1991 CENPJ 4 72 1.637624e-01 0.773246969
BCAR1 175 BCAR1 4 72 1.637624e-01 0.773246969
CHEK1 1552 CHEK1 2 25 1.680502e-01 1.252958148
NPM1 1649 NPM1 2 25 1.680502e-01 1.252958148
TAF1B 2025 TAF1B 2 25 1.680502e-01 1.252958148
TAF1C 2026 TAF1C 2 25 1.680502e-01 1.252958148
AHR 1303 AHR 2 25 1.680502e-01 1.252958148
SH2B2 104 SH2B2 2 25 1.680502e-01 1.252958148
CD19 5771 CD19 2 25 1.680502e-01 1.252958148
NFATC1 122 NFATC1 2 25 1.680502e-01 1.252958148
MAP2K1 850 MAP2K1 3 48 1.687283e-01 0.929938499
SIN3B 2584 SIN3B 3 48 1.687283e-01 0.929938499
EPOR 1596 EPOR 3 48 1.687283e-01 0.929938499
RBBP4 1320 RBBP4 4 73 1.695170e-01 0.758641873
NUP210 3931 NUP210 4 73 1.695170e-01 0.758641873
NFKB1 2606 NFKB1 6 126 1.696610e-01 0.577731585
TYK2 23 TYK2 5 100 1.740837e-01 0.642298055
PSMD10 2316 PSMD10 4 74 1.753420e-01 0.744243814
NUP54 3098 NUP54 4 74 1.753420e-01 0.744243814
RAE1 3204 RAE1 4 74 1.753420e-01 0.744243814
PCM1 5376 PCM1 4 74 1.753420e-01 0.744243814
MCM2 5254 MCM2 3 49 1.760692e-01 0.908086712
GEMIN4 1475 GEMIN4 3 49 1.760692e-01 0.908086712
SIP1 2091 SIP1 3 49 1.760692e-01 0.908086712
MAPK3 172 MAPK3 6 128 1.783638e-01 0.561044804
TAF1A 489 TAF1A 2 26 1.786972e-01 1.211173925
HIPK2 1846 HIPK2 2 26 1.786972e-01 1.211173925
SPI1 148 SPI1 2 26 1.786972e-01 1.211173925
SUV39H1 1301 SUV39H1 2 26 1.786972e-01 1.211173925
GSN 5019 GSN 2 26 1.786972e-01 1.211173925
SNAPC5 3887 SNAPC5 2 26 1.786972e-01 1.211173925
IL18 7719 IL18 2 26 1.786972e-01 1.211173925
APOE 874 APOE 2 26 1.786972e-01 1.211173925
TRIM24 1216 TRIM24 2 26 1.786972e-01 1.211173925
SMAD9 858 SMAD9 5 101 1.790616e-01 0.631768865
POLA1 306 POLA1 3 50 1.834974e-01 0.886697500
CDC25A 4739 CDC25A 2 27 1.894441e-01 1.171057052
RRAS2 482 RRAS2 2 27 1.894441e-01 1.171057052
HSPG2 3012 HSPG2 2 27 1.894441e-01 1.171057052
UBE3A 1365 UBE3A 3 51 1.910076e-01 0.865751588
MAPK8 71 MAPK8 6 131 1.917477e-01 0.536511723
CEP70 5736 CEP70 4 77 1.932130e-01 0.702234738
PIAS1 252 PIAS1 3 52 1.985944e-01 0.845230878
CD3G 1651 CD3G 3 52 1.985944e-01 0.845230878
HDAC2 1347 HDAC2 5 105 1.994892e-01 0.590704303
ERBB4 57 ERBB4 2 28 2.002757e-01 1.132479220
NCL 2322 NCL 2 28 2.002757e-01 1.132479220
CCNA2 3404 CCNA2 2 28 2.002757e-01 1.132479220
CEBPA 4208 CEBPA 2 28 2.002757e-01 1.132479220
MAP2K6 2775 MAP2K6 2 28 2.002757e-01 1.132479220
EXOSC6 1950 EXOSC6 2 28 2.002757e-01 1.132479220
SAP30 2578 SAP30 3 53 2.062525e-01 0.825118361
INPP5D 113 INPP5D 3 53 2.062525e-01 0.825118361
GRAP2 98 GRAP2 3 53 2.062525e-01 0.825118361
CD3D 1633 CD3D 3 53 2.062525e-01 0.825118361
DDX20 18 DDX20 3 53 2.062525e-01 0.825118361
TSG101 2010 TSG101 2 29 2.111777e-01 1.095326384
TRAM2 1810 TRAM2 2 29 2.111777e-01 1.095326384
ALDH1A1 7121 ALDH1A1 2 29 2.111777e-01 1.095326384
EPO 7701 EPO 2 29 2.111777e-01 1.095326384
BANF1 1721 BANF1 2 29 2.111777e-01 1.095326384
PLAU 566 PLAU 2 29 2.111777e-01 1.095326384
SMPD1 2430 SMPD1 2 29 2.111777e-01 1.095326384
PIAS3 2992 PIAS3 2 29 2.111777e-01 1.095326384
ITGA3 2407 ITGA3 2 29 2.111777e-01 1.095326384
ABCA1 2590 ABCA1 2 29 2.111777e-01 1.095326384
MAGEA11 5358 MAGEA11 3 54 2.139768e-01 0.805398027
HGS 499 HGS 3 54 2.139768e-01 0.805398027
BMPR1B 1921 BMPR1B 3 54 2.139768e-01 0.805398027
CSNK1E 703 CSNK1E 4 81 2.178682e-01 0.648793526
TUBA4A 973 TUBA4A 5 109 2.206685e-01 0.551224914
CASP7 832 CASP7 3 55 2.217622e-01 0.786054789
DOK2 2721 DOK2 2 30 2.221364e-01 1.059496726
TFDP1 7611 TFDP1 2 30 2.221364e-01 1.059496726
STUB1 3432 STUB1 2 30 2.221364e-01 1.059496726
CD79B 2996 CD79B 2 30 2.221364e-01 1.059496726
SUFU 283 SUFU 2 30 2.221364e-01 1.059496726
RAF1 1735 RAF1 5 110 2.260691e-01 0.541588490
TAF9 1797 TAF9 3 56 2.296036e-01 0.767074417
IL12RB2 2918 IL12RB2 3 56 2.296036e-01 0.767074417
RXRA 448 RXRA 4 83 2.305033e-01 0.623090024
SFN 1947 SFN 2 31 2.331391e-01 1.024898961
EPS15 2418 EPS15 2 31 2.331391e-01 1.024898961
RAD51 3421 RAD51 2 31 2.331391e-01 1.024898961
GRIN2D 1044 GRIN2D 2 31 2.331391e-01 1.024898961
ATF2 4203 ATF2 2 31 2.331391e-01 1.024898961
GNAO1 6071 GNAO1 2 31 2.331391e-01 1.024898961
PTPN12 1828 PTPN12 2 31 2.331391e-01 1.024898961
IL6 6078 IL6 2 31 2.331391e-01 1.024898961
CREBBP 202 CREBBP 8 199 2.364652e-01 0.382197469
HD 1647 HD 3 57 2.374961e-01 0.748443468
BRCA1 3524 BRCA1 5 113 2.424989e-01 0.513211565
PLD2 540 PLD2 2 32 2.441736e-01 0.991450940
MAP4K1 1924 MAP4K1 2 32 2.441736e-01 0.991450940
RBL2 759 RBL2 2 32 2.441736e-01 0.991450940
KITLG 88 KITLG 2 32 2.441736e-01 0.991450940
RET 1547 RET 2 32 2.441736e-01 0.991450940
SH3GL3 2145 SH3GL3 2 32 2.441736e-01 0.991450940
USHBP1 4534 USHBP1 2 32 2.441736e-01 0.991450940
HSPA8 78 HSPA8 3 58 2.454348e-01 0.730149236
SFRS1 1662 SFRS1 6 143 2.487199e-01 0.443839009
NUP62 1727 NUP62 4 86 2.497820e-01 0.585712034
CDC2 1954 CDC2 8 203 2.529050e-01 0.361070198
IL12A 6559 IL12A 3 59 2.534151e-01 0.712179693
IGF1R 4749 IGF1R 3 59 2.534151e-01 0.712179693
MXD1 1690 MXD1 2 33 2.552285e-01 0.959078465
CDC7 2679 CDC7 2 33 2.552285e-01 0.959078465
APEX1 969 APEX1 2 33 2.552285e-01 0.959078465
PTMA 773 PTMA 2 33 2.552285e-01 0.959078465
NEDD4 2434 NEDD4 2 33 2.552285e-01 0.959078465
GNA13 1045 GNA13 2 33 2.552285e-01 0.959078465
CSNK2A1 911 CSNK2A1 7 174 2.562856e-01 0.389917330
LCK 103 LCK 6 145 2.586654e-01 0.429172388
JAK1 595 JAK1 5 116 2.592375e-01 0.485599328
PML 3915 PML 3 60 2.614321e-01 0.694523445
NXF1 2084 NXF1 3 60 2.614321e-01 0.694523445
VAV1 25 VAV1 4 88 2.628218e-01 0.561534250
RANBP2 2481 RANBP2 6 146 2.636782e-01 0.421916512
PRKCD 276 PRKCD 5 117 2.648782e-01 0.476558066
BCR 1642 BCR 2 34 2.662930e-01 0.927714295
RBL1 4702 RBL1 2 34 2.662930e-01 0.927714295
CASP10 2056 CASP10 2 34 2.662930e-01 0.927714295
IGHE 7717 IGHE 2 34 2.662930e-01 0.927714295
DLG3 2226 DLG3 2 34 2.662930e-01 0.927714295
AR 201 AR 6 147 2.687162e-01 0.414711283
CSK 1381 CSK 3 61 2.694814e-01 0.677169688
NCOA1 220 NCOA1 3 61 2.694814e-01 0.677169688
EIF2AK2 625 EIF2AK2 2 35 2.773567e-01 0.897297307
ZHX1 1699 ZHX1 2 35 2.773567e-01 0.897297307
CD79A 5777 CD79A 2 35 2.773567e-01 0.897297307
CD4 19 CD4 5 120 2.819613e-01 0.449902786
PTPN1 626 PTPN1 3 63 2.856591e-01 0.643329138
KPNB1 429 KPNB1 3 63 2.856591e-01 0.643329138
CDC45L 2520 CDC45L 2 36 2.884102e-01 0.867771771
UTP14A 2148 UTP14A 2 36 2.884102e-01 0.867771771
NCOA6 687 NCOA6 2 36 2.884102e-01 0.867771771
DLG2 724 DLG2 2 36 2.884102e-01 0.867771771
GADD45G 455 GADD45G 2 36 2.884102e-01 0.867771771
GTF3C1 4353 GTF3C1 2 36 2.884102e-01 0.867771771
PAFAH1B1 1294 PAFAH1B1 6 151 2.890977e-01 0.386382783
FASLG 1602 FASLG 3 64 2.937788e-01 0.626823340
IL2RA 4656 IL2RA 3 64 2.937788e-01 0.626823340
GFI1B 6556 GFI1B 3 64 2.937788e-01 0.626823340
BIRC5 2946 BIRC5 4 93 2.959309e-01 0.503485582
C1orf103 2822 C1orf103 4 93 2.959309e-01 0.503485582
FCER1A 4803 FCER1A 2 37 2.994445e-01 0.839086736
PLCG2 142 PLCG2 2 37 2.994445e-01 0.839086736
MAP3K1 7361 MAP3K1 2 37 2.994445e-01 0.839086736
MYOC 5960 MYOC 2 37 2.994445e-01 0.839086736
IL2RB 1648 IL2RB 3 65 3.019136e-01 0.610581957
GTF2B 79 GTF2B 3 65 3.019136e-01 0.610581957
PPP2R1A 2966 PPP2R1A 4 94 3.026205e-01 0.492262004
AP2A1 1404 AP2A1 2 38 3.104509e-01 0.811195496
AURKA 2018 AURKA 2 38 3.104509e-01 0.811195496
JUP 431 JUP 2 38 3.104509e-01 0.811195496
KHDRBS1 173 KHDRBS1 2 38 3.104509e-01 0.811195496
GNAQ 508 GNAQ 2 38 3.104509e-01 0.811195496
PRMT5 957 PRMT5 2 38 3.104509e-01 0.811195496
ACTN2 4748 ACTN2 2 38 3.104509e-01 0.811195496
LYN 82 LYN 5 125 3.108759e-01 0.406960024
GTF2H1 474 GTF2H1 4 96 3.160488e-01 0.470178465
MAPK14 264 MAPK14 5 126 3.167112e-01 0.398582768
KIAA1377 2154 KIAA1377 3 67 3.182121e-01 0.578859251
MMP9 4176 MMP9 2 39 3.214215e-01 0.784055135
TAF4B 6362 TAF4B 2 39 3.214215e-01 0.784055135
HSPA5 758 HSPA5 2 39 3.214215e-01 0.784055135
CDK9 2425 CDK9 3 68 3.263681e-01 0.563362293
JAK3 1645 JAK3 3 68 3.263681e-01 0.563362293
CTNNB1 3569 CTNNB1 6 159 3.307335e-01 0.331953427
KPNA2 392 KPNA2 2 40 3.323488e-01 0.757626126
KPNA1 393 KPNA1 2 40 3.323488e-01 0.757626126
MS4A2 1652 MS4A2 2 40 3.323488e-01 0.757626126
GTF2A2 1783 GTF2A2 2 40 3.323488e-01 0.757626126
TAF13 2636 TAF13 2 40 3.323488e-01 0.757626126
NEK2 997 NEK2 5 129 3.342947e-01 0.373853001
COPS6 2049 COPS6 3 70 3.426752e-01 0.533060723
CAMK2A 465 CAMK2A 2 41 3.432258e-01 0.731871983
ADRBK1 1375 ADRBK1 2 41 3.432258e-01 0.731871983
FOXA2 2701 FOXA2 2 41 3.432258e-01 0.731871983
TGFB1 1447 TGFB1 2 41 3.432258e-01 0.731871983
PAK2 1402 PAK2 2 41 3.432258e-01 0.731871983
SFRS7 3854 SFRS7 5 131 3.460668e-01 0.357690803
TUBB 1069 TUBB 4 101 3.497993e-01 0.416972650
SUMO4 5963 SUMO4 3 71 3.508190e-01 0.518242500
CLASP1 4287 CLASP1 5 132 3.519634e-01 0.349703924
MYOD1 568 MYOD1 2 42 3.540460e-01 0.706758955
TAF5 1807 TAF5 2 42 3.540460e-01 0.706758955
GTF2E1 6636 GTF2E1 2 42 3.540460e-01 0.706758955
MNAT1 1316 MNAT1 4 102 3.565628e-01 0.406656025
NDE1 3451 NDE1 5 133 3.578651e-01 0.341778549
CAPN1 3659 CAPN1 2 43 3.648032e-01 0.682255764
UGDH 6178 UGDH 2 43 3.648032e-01 0.682255764
MBP 3380 MBP 2 43 3.648032e-01 0.682255764
FCER1G 5077 FCER1G 2 43 3.648032e-01 0.682255764
TAF6 1787 TAF6 2 43 3.648032e-01 0.682255764
TAF12 2541 TAF12 2 43 3.648032e-01 0.682255764
NRIP1 218 NRIP1 2 43 3.648032e-01 0.682255764
XRCC6 935 XRCC6 3 73 3.670706e-01 0.489239345
RAN 1269 RAN 3 73 3.670706e-01 0.489239345
CASP3 168 CASP3 5 135 3.696785e-01 0.326108519
CKAP5 3502 CKAP5 5 135 3.696785e-01 0.326108519
YWHAE 1894 YWHAE 5 135 3.696785e-01 0.326108519
EIF4E 3542 EIF4E 4 104 3.700867e-01 0.386329899
MAPT 3764 MAPT 2 44 3.754916e-01 0.658333364
GTF2A1 1784 GTF2A1 2 44 3.754916e-01 0.658333364
MAPRE1 709 MAPRE1 5 136 3.755873e-01 0.318362021
UBE2I 244 UBE2I 4 105 3.768430e-01 0.376316336
TRAF2 1341 TRAF2 6 168 3.783848e-01 0.273957029
CD247 972 CD247 3 75 3.832525e-01 0.461041252
EP300 221 EP300 7 201 3.845512e-01 0.237403643
TAF11 1376 TAF11 2 45 3.861059e-01 0.634964739
FEZ1 378 FEZ1 2 45 3.861059e-01 0.634964739
GRIN1 1050 GRIN1 2 46 3.966411e-01 0.612124713
TAF10 2540 TAF10 2 46 3.966411e-01 0.612124713
ZBTB16 1374 ZBTB16 3 77 3.993407e-01 0.433604398
NUP85 7435 NUP85 5 141 4.051001e-01 0.280479701
TAF4 1774 TAF4 2 47 4.070927e-01 0.589789788
SAT1 5370 SAT1 2 48 4.174564e-01 0.567938001
COIL 1462 COIL 2 48 4.174564e-01 0.567938001
HGF 5785 HGF 2 48 4.174564e-01 0.567938001
INS 118 INS 3 80 4.232487e-01 0.393789057
HDAC1 763 HDAC1 6 177 4.261743e-01 0.219031760
GNAI2 3561 GNAI2 2 49 4.277282e-01 0.546548789
CDK5 2179 CDK5 2 49 4.277282e-01 0.546548789
DNM1 731 DNM1 2 49 4.277282e-01 0.546548789
SNRPD2 2799 SNRPD2 5 145 4.285963e-01 0.251144951
U2AF2 2080 U2AF2 5 146 4.344445e-01 0.243939722
FAS 3752 FAS 2 50 4.379045e-01 0.525602877
MAX 5302 MAX 2 50 4.379045e-01 0.525602877
CSNK1A1 1267 CSNK1A1 2 50 4.379045e-01 0.525602877
CSNK2B 4197 CSNK2B 2 50 4.379045e-01 0.525602877
IRS1 1658 IRS1 3 82 4.390082e-01 0.368085555
ARNT 733 ARNT 3 82 4.390082e-01 0.368085555
APP 1099 APP 3 83 4.468271e-01 0.355473165
IL2RG 2240 IL2RG 3 83 4.468271e-01 0.355473165
ATN1 329 ATN1 3 83 4.468271e-01 0.355473165
POLR2F 4151 POLR2F 6 181 4.472776e-01 0.195522315
CTBP1 1315 CTBP1 2 51 4.479819e-01 0.505082167
DOK1 96 DOK1 2 51 4.479819e-01 0.505082167
ARF1 4815 ARF1 2 52 4.579574e-01 0.484969650
POU2F1 4979 POU2F1 2 52 4.579574e-01 0.484969650
POLR2E 1809 POLR2E 6 184 4.630011e-01 0.178232370
TRAF6 1087 TRAF6 4 118 4.634568e-01 0.254336760
SOCS3 806 SOCS3 2 53 4.678282e-01 0.465249315
PRKCE 275 PRKCE 2 53 4.678282e-01 0.465249315
POLR2L 5303 POLR2L 6 185 4.682182e-01 0.172532275
GAB2 181 GAB2 2 54 4.775917e-01 0.445906078
PRKCZ 1006 PRKCZ 3 87 4.776484e-01 0.306529781
INSR 2821 INSR 3 87 4.776484e-01 0.306529781
FN1 4672 FN1 3 88 4.852305e-01 0.294652649
NCBP1 4931 NCBP1 5 155 4.863804e-01 0.181258773
ARRB2 4825 ARRB2 2 55 4.872456e-01 0.426925705
HLA-A 2865 HLA-A 2 55 4.872456e-01 0.426925705
VAMP2 7637 VAMP2 2 55 4.872456e-01 0.426925705
BMPR2 1867 BMPR2 2 55 4.872456e-01 0.426925705
LRP1 861 LRP1 2 56 4.967879e-01 0.408294757
ERCC3 6346 ERCC3 3 90 5.002347e-01 0.271305613
ACVR1 3202 ACVR1 2 57 5.062167e-01 0.390000525
POLR2H 4737 POLR2H 6 193 5.094119e-01 0.128020269
POLR2K 3503 POLR2K 6 194 5.144827e-01 0.122587503
CPSF2 7199 CPSF2 4 126 5.146755e-01 0.185898839
YWHAB 457 YWHAB 4 126 5.146755e-01 0.185898839
CREB1 4842 CREB1 2 58 5.155304e-01 0.372030982
GTF2F2 197 GTF2F2 5 161 5.200705e-01 0.141486884
SFRS11 2090 SFRS11 4 127 5.209231e-01 0.177655942
CPSF3 7200 CPSF3 4 127 5.209231e-01 0.177655942
DHX38 7233 DHX38 4 127 5.209231e-01 0.177655942
PSMA3 3959 PSMA3 3 93 5.223180e-01 0.237257534
TERT 1009 TERT 2 59 5.247274e-01 0.354374734
DAXX 394 DAXX 2 59 5.247274e-01 0.354374734
HCK 4621 HCK 2 59 5.247274e-01 0.354374734
PSEN1 5770 PSEN1 2 59 5.247274e-01 0.354374734
CDC40 4313 CDC40 4 128 5.271328e-01 0.169478598
SFRS6 7558 SFRS6 4 128 5.271328e-01 0.169478598
PPP1CC 841 PPP1CC 3 94 5.295608e-01 0.226156047
MAGOH 6837 MAGOH 4 129 5.333036e-01 0.161365758
B2M 2338 B2M 2 60 5.338066e-01 0.337020976
RBM8A 3833 RBM8A 4 130 5.394347e-01 0.153316399
PDPK1 654 PDPK1 2 61 5.427667e-01 0.319959455
POLA2 4575 POLA2 2 61 5.427667e-01 0.319959455
SFRS5 4922 SFRS5 4 131 5.455250e-01 0.145329521
UPF3B 7630 UPF3B 4 131 5.455250e-01 0.145329521
SFRS9 2568 SFRS9 4 132 5.515738e-01 0.137404146
SRRM1 4293 SRRM1 4 132 5.515738e-01 0.137404146
U2AF1 6551 U2AF1 4 132 5.515738e-01 0.137404146
RBX1 418 RBX1 2 62 5.516070e-01 0.303180427
CPSF1 4729 CPSF1 4 133 5.575803e-01 0.129539321
CCNH 1790 CCNH 3 98 5.579085e-01 0.182919182
SUMO1 216 SUMO1 2 63 5.603266e-01 0.286674628
NCOR2 449 NCOR2 2 63 5.603266e-01 0.286674628
IKBKG 1994 IKBKG 2 63 5.603266e-01 0.286674628
SFRS4 3830 SFRS4 4 134 5.635436e-01 0.121734115
ZAP70 298 ZAP70 2 64 5.689249e-01 0.270433246
CDK7 1823 CDK7 3 100 5.716941e-01 0.161968181
SFRS3 2567 SFRS3 4 136 5.753382e-01 0.106298938
RNPS1 3984 RNPS1 4 136 5.753382e-01 0.106298938
NUP43 7434 NUP43 4 136 5.753382e-01 0.106298938
RAC1 491 RAC1 4 136 5.753382e-01 0.106298938
RIPK1 2057 RIPK1 2 65 5.774015e-01 0.254447883
NUP133 3201 NUP133 4 137 5.811681e-01 0.098667206
NUP37 4658 NUP37 4 137 5.811681e-01 0.098667206
NUP160 7431 NUP160 4 137 5.811681e-01 0.098667206
ITGAV 372 ITGAV 2 66 5.857559e-01 0.238710539
HADH 7311 HADH 2 66 5.857559e-01 0.238710539
SFRS2 2083 SFRS2 4 138 5.869521e-01 0.091091574
SNRPD1 1466 SNRPD1 4 139 5.926897e-01 0.083571208
SMAD4 207 SMAD4 6 211 5.972174e-01 0.034306230
SNRPF 3249 SNRPF 4 140 5.983804e-01 0.076105297
SYK 29 SYK 3 104 5.984559e-01 0.121311867
GNB2L1 530 GNB2L1 2 68 6.020977e-01 0.207949726
ATXN1 2472 ATXN1 4 142 6.096189e-01 0.061333674
AURKB 3890 AURKB 3 106 6.114219e-01 0.101574030
SNRPD3 1465 SNRPD3 4 143 6.151658e-01 0.054026423
PRPF6 2507 PRPF6 3 109 6.303415e-01 0.072663029
SNRPG 5444 SNRPG 4 146 6.315115e-01 0.032410023
CDC27 5086 CDC27 2 72 6.333141e-01 0.149090634
TNF 1110 TNF 2 72 6.333141e-01 0.149090634
ATP5C1 5128 ATP5C1 3 110 6.365055e-01 0.063204598
NHP2L1 5398 NHP2L1 3 110 6.365055e-01 0.063204598
NUDT21 5481 NUDT21 3 111 6.425977e-01 0.053832692
CSNK2A2 1468 CSNK2A2 2 74 6.481929e-01 0.120892541
EIF2S2 2882 EIF2S2 2 74 6.481929e-01 0.120892541
NCBP2 2854 NCBP2 4 150 6.526053e-01 0.004274412
RBMX 5352 RBMX 3 113 6.545664e-01 0.035342144
GSK3B 416 GSK3B 2 75 6.554515e-01 0.107081558
ZW10 7648 ZW10 2 75 6.554515e-01 0.107081558
UNC119 176 UNC119 2 75 6.554515e-01 0.107081558
SNRPB 6107 SNRPB 4 151 6.577518e-01 -0.002641413
YWHAQ 1293 YWHAQ 2 76 6.625905e-01 0.093455687
UBE2D1 3480 UBE2D1 2 76 6.625905e-01 0.093455687
POLR2I 7477 POLR2I 4 153 6.678907e-01 -0.016335823
PSMC3 3962 PSMC3 2 77 6.696105e-01 0.080009992
CCDC85B 5728 CCDC85B 3 116 6.719782e-01 0.008216933
PSMB5 5843 PSMB5 2 78 6.765123e-01 0.066739730
CUL1 1818 CUL1 2 78 6.765123e-01 0.066739730
CDK2 3390 CDK2 4 155 6.778234e-01 -0.029851299
POLR2J 3649 POLR2J 4 155 6.778234e-01 -0.029851299
POLR2B 4799 POLR2B 4 155 6.778234e-01 -0.029851299
CALM1 1804 CALM1 4 156 6.827120e-01 -0.036543412
POLR2D 4570 POLR2D 4 156 6.827120e-01 -0.036543412
SEC13 7552 SEC13 2 79 6.832967e-01 0.053640346
GTF2F1 1788 GTF2F1 4 157 6.875488e-01 -0.043192537
RPA1 772 RPA1 2 80 6.899646e-01 0.040707455
SETDB1 151 SETDB1 2 80 6.899646e-01 0.040707455
PSMC2 5795 PSMC2 2 80 6.899646e-01 0.040707455
POLR2G 4469 POLR2G 4 158 6.923335e-01 -0.049799233
CDCA8 4019 CDCA8 2 82 7.029546e-01 0.015324454
SKIL 4730 SKIL 2 82 7.029546e-01 0.015324454
YBX1 615 YBX1 3 122 7.048550e-01 -0.043972734
RANGAP1 3275 RANGAP1 2 84 7.154903e-01 -0.009441147
PSMC5 1354 PSMC5 2 84 7.154903e-01 -0.009441147
TGFBR1 28 TGFBR1 4 164 7.199499e-01 -0.088578350
POLR2C 4332 POLR2C 4 164 7.199499e-01 -0.088578350
NDC80 1334 NDC80 2 85 7.215905e-01 -0.021601751
GTF2H4 1786 GTF2H4 2 85 7.215905e-01 -0.021601751
GTF2H3 6638 GTF2H3 2 85 7.215905e-01 -0.021601751
DHX9 226 DHX9 3 126 7.253432e-01 -0.077348528
INCENP 4018 INCENP 2 86 7.275804e-01 -0.033618931
GTF2H2 6353 GTF2H2 2 86 7.275804e-01 -0.033618931
ERCC2 4720 ERCC2 2 88 7.392340e-01 -0.057236403
ACTA1 6578 ACTA1 2 89 7.449001e-01 -0.068843098
CASP8 833 CASP8 2 91 7.559170e-01 -0.091667599
UBQLN4 3119 UBQLN4 3 134 7.629734e-01 -0.141016852
ATP5D 7144 ATP5D 2 93 7.665220e-01 -0.113992665
ATP5E 7145 ATP5E 2 93 7.665220e-01 -0.113992665
ATP5F1 7146 ATP5F1 2 93 7.665220e-01 -0.113992665
ATP5G1 7147 ATP5G1 2 93 7.665220e-01 -0.113992665
ATP5I 7148 ATP5I 2 93 7.665220e-01 -0.113992665
ATP5O 7151 ATP5O 2 93 7.665220e-01 -0.113992665
EEF2 7247 EEF2 2 94 7.716734e-01 -0.124974715
RPL11 3749 RPL11 2 94 7.716734e-01 -0.124974715
ATP5H 6328 ATP5H 2 94 7.716734e-01 -0.124974715
ATP5L 7150 ATP5L 2 94 7.716734e-01 -0.124974715
ATP5J 7149 ATP5J 2 95 7.767257e-01 -0.135839898
SMAD2 210 SMAD2 4 179 7.809016e-01 -0.179623650
PSMD11 5465 PSMD11 2 96 7.816802e-01 -0.146590700
XPO1 1273 XPO1 3 140 7.883759e-01 -0.186311424
ATP5A1 6771 ATP5A1 2 98 7.913015e-01 -0.167758720
ACTB 4481 ACTB 2 99 7.959709e-01 -0.178180531
RPL18A 253 RPL18A 2 99 7.959709e-01 -0.178180531
ATP5B 6038 ATP5B 2 100 8.005480e-01 -0.188497155
SNRNP70 7588 SNRNP70 2 100 8.005480e-01 -0.188497155
POLR2A 1836 POLR2A 4 187 8.088608e-01 -0.225107230
AASS 7078 AASS 2 103 8.137387e-01 -0.218836844
SNRPA1 2853 SNRPA1 2 103 8.137387e-01 -0.218836844
SNRPA 5331 SNRPA 2 103 8.137387e-01 -0.218836844
CLP1 5748 CLP1 2 103 8.137387e-01 -0.218836844
CPSF7 7201 CPSF7 2 103 8.137387e-01 -0.218836844
CSTF3 7207 CSTF3 2 103 8.137387e-01 -0.218836844
DDX23 7227 DDX23 2 103 8.137387e-01 -0.218836844
DNAJC8 7237 DNAJC8 2 103 8.137387e-01 -0.218836844
HNRNPA0 7322 HNRNPA0 2 103 8.137387e-01 -0.218836844
HNRNPA1 7323 HNRNPA1 2 103 8.137387e-01 -0.218836844
HNRNPA2B1 7324 HNRNPA2B1 2 103 8.137387e-01 -0.218836844
HNRNPA3 7325 HNRNPA3 2 103 8.137387e-01 -0.218836844
HNRNPD 7327 HNRNPD 2 103 8.137387e-01 -0.218836844
HNRNPF 7328 HNRNPF 2 103 8.137387e-01 -0.218836844
HNRNPH1 7329 HNRNPH1 2 103 8.137387e-01 -0.218836844
HNRNPH2 7330 HNRNPH2 2 103 8.137387e-01 -0.218836844
HNRNPL 7331 HNRNPL 2 103 8.137387e-01 -0.218836844
HNRNPM 7332 HNRNPM 2 103 8.137387e-01 -0.218836844
HNRNPR 7333 HNRNPR 2 103 8.137387e-01 -0.218836844
HNRNPU 7334 HNRNPU 2 103 8.137387e-01 -0.218836844
HNRNPUL1 7335 HNRNPUL1 2 103 8.137387e-01 -0.218836844
PCF11 7446 PCF11 2 103 8.137387e-01 -0.218836844
PHF5A 7459 PHF5A 2 103 8.137387e-01 -0.218836844
SF3B14 7555 SF3B14 2 103 8.137387e-01 -0.218836844
SF3B5 7556 SF3B5 2 103 8.137387e-01 -0.218836844
SF4 7557 SF4 2 103 8.137387e-01 -0.218836844
SNRNP200 7586 SNRNP200 2 103 8.137387e-01 -0.218836844
SNRNP40 7587 SNRNP40 2 103 8.137387e-01 -0.218836844
ATP5J2 6329 ATP5J2 2 104 8.179599e-01 -0.228753349
RBM5 5496 RBM5 2 104 8.179599e-01 -0.228753349
PRPF8 7487 PRPF8 2 104 8.179599e-01 -0.228753349
RPL5 2695 RPL5 2 105 8.220956e-01 -0.238574681
SF3A3 2087 SF3A3 2 105 8.220956e-01 -0.238574681
SNRPB2 2424 SNRPB2 2 105 8.220956e-01 -0.238574681
TXNL4A 2473 TXNL4A 2 105 8.220956e-01 -0.238574681
CSTF1 2816 CSTF1 2 105 8.220956e-01 -0.238574681
CCAR1 3365 CCAR1 2 105 8.220956e-01 -0.238574681
SF3B2 4595 SF3B2 2 105 8.220956e-01 -0.238574681
EFTUD2 6192 EFTUD2 2 105 8.220956e-01 -0.238574681
PAPOLA 1486 PAPOLA 2 106 8.261470e-01 -0.248302670
CD2BP2 1691 CD2BP2 2 106 8.261470e-01 -0.248302670
SF3A2 2422 SF3A2 2 106 8.261470e-01 -0.248302670
SF3A1 1766 SF3A1 2 107 8.301155e-01 -0.257939095
PRPF4 3059 PRPF4 2 107 8.301155e-01 -0.257939095
PABPN1 3517 PABPN1 2 107 8.301155e-01 -0.257939095
HNRNPC 7326 HNRNPC 2 107 8.301155e-01 -0.257939095
SF3B3 4297 SF3B3 2 108 8.340025e-01 -0.267485682
PCBP2 2988 PCBP2 2 109 8.378093e-01 -0.276944113
SF3B4 4468 SF3B4 2 110 8.415371e-01 -0.286316019
SF3B1 665 SF3B1 2 111 8.451874e-01 -0.295602989
PTBP1 3964 PTBP1 2 113 8.522604e-01 -0.313928256
VIM 439 VIM 2 113 8.522604e-01 -0.313928256
RPS7 3919 RPS7 2 115 8.590386e-01 -0.331931778
SMAD1 287 SMAD1 2 115 8.590386e-01 -0.331931778
CSTF2 2815 CSTF2 2 117 8.655322e-01 -0.349624798
LSM2 2801 LSM2 2 118 8.686754e-01 -0.358358223
SMC1A 3442 SMC1A 2 121 8.777055e-01 -0.384121445
PCBP1 3825 PCBP1 2 122 8.805863e-01 -0.392567560
RPS3A 677 RPS3A 2 124 8.861614e-01 -0.409254341
BUB3 683 BUB3 2 134 9.105961e-01 -0.488854243
BUB1B 2675 BUB1B 2 138 9.189235e-01 -0.519047884
MAD2L1 4732 MAD2L1 2 139 9.208887e-01 -0.526460136
CDC20 1684 CDC20 2 142 9.265195e-01 -0.548382633
EEF1G 4003 EEF1G 2 142 9.265195e-01 -0.548382633
EEF1A1 4955 EEF1A1 2 168 9.617369e-01 -0.721112631
RPS27 6187 RPS27 2 186 9.759232e-01 -0.825808759
pValueFDR
CRK 0.01866731
IFNAR1 0.01866731
CBL 0.01934293
GAB1 0.04887827
CDK6 0.04887827
PTPN11 0.04887827
NRCAM 0.06104535
EGF 0.06238645
E4F1 0.06238645
UBE2A 0.06238645
CCNG1 0.06238645
SH3BGRL3 0.06238645
IFNAR2 0.06238645
CCND1 0.07034416
SOS1 0.07886132
YES1 0.07886132
FES 0.07886132
IL1B 0.07886132
EPB41L1 0.07886132
CRKL 0.07886132
MAP2K3 0.07886132
GRB2 0.07886132
GRB7 0.07886132
NUMA1 0.07886132
ERRFI1 0.07886132
TRIAP1 0.07886132
TIE1 0.07886132
KCNE4 0.07886132
CELSR2 0.07886132
PDGFRB 0.10416353
SHB 0.11801640
RAP1A 0.11801640
IL1R1 0.11801640
BTC 0.11801640
ZNHIT1 0.11801640
NQO1 0.11801640
PTPRO 0.11801640
ECM1 0.11801640
SH3KBP1 0.12615946
RAD54B 0.12866809
PIK3R2 0.12866809
STAT5B 0.12866809
PTK2 0.12866809
SOCS1 0.13166199
ITGB4 0.13566435
ANGPT2 0.14093742
TEC 0.14093742
PIK3C2A 0.14093742
SERTAD1 0.14093742
MAGEB18 0.14093742
MTSS1 0.14093742
GTPBP3 0.14093742
PIK3CB 0.14504880
SNX6 0.14504880
PHB 0.14504880
VAV2 0.15815670
VEGFA 0.15852148
SMARCB1 0.15852148
NFYB 0.15852148
SERPINA3 0.15852148
KLF4 0.15852148
MNDA 0.15852148
EID1 0.15852148
CREG1 0.15852148
SERPINB2 0.15852148
CNTNAP1 0.15852148
CNOT3 0.15852148
IFNGR2 0.15852148
GRB14 0.15853366
MSX1 0.15853366
EHMT2 0.15853366
L1CAM 0.15853366
STAT5A 0.16643761
HDAC3 0.16643761
CDKN1A 0.16643761
E2F1 0.16746519
DLG1 0.16746519
CBLB 0.16746519
GRB10 0.16746519
CBLC 0.16746519
SCAMP1 0.16746519
KRT7 0.16746519
SOCS5 0.16746519
PGF 0.16746519
RND1 0.16746519
NAGK 0.16746519
CNOT8 0.16746519
NCAN 0.16746519
HSP90AA1 0.16746519
IL23A 0.16746519
IL23R 0.16746519
MAPKAPK5 0.16746519
FGFR2 0.16746519
HMGB1 0.17335896
GFRA1 0.17721384
GDNF 0.17721384
PTPRS 0.17929997
BAG1 0.17929997
ITCH 0.17929997
HCFC1 0.17929997
PPP1CA 0.18225429
HUWE1 0.18281173
ZCCHC10 0.18281173
CSF2RA 0.18281173
DUSP16 0.18281173
STAT3 0.18281173
NGF 0.18281173
CD82 0.18281173
PTPN2 0.18281173
BDNF 0.18281173
CDC37 0.18281173
FYN 0.18281173
MET 0.18768125
SP3 0.18768125
HSP90AB1 0.18768125
TBX21 0.18768125
RAPGEF1 0.18768125
NT5C2 0.18768125
SNAPC1 0.18768125
HIF1A 0.18768125
CCND3 0.18768125
FGFR1 0.18768125
SNX4 0.18768125
CR2 0.18768125
CBX8 0.18768125
PDGFA 0.18768125
ELF1 0.18768125
TUB 0.18768125
CSPG4 0.18768125
SUB1 0.18768125
SDC2 0.18969672
SP1 0.18969672
FER 0.19629420
BCL2L1 0.19855948
NCK2 0.20628505
HIST3H3 0.20628505
MAP2K4 0.20628505
TRAT1 0.20628505
PRKRA 0.20628505
CNOT7 0.20628505
PJA1 0.20628505
PDGFB 0.20628505
DTX1 0.20628505
ADAM10 0.20628505
CNTN1 0.20628505
ITGB1 0.20712836
CDH1 0.20712836
ITGA6 0.20712836
ITGA4 0.20712836
FOS 0.20712836
BRF1 0.20712836
CSF2RB 0.20712836
TIAM1 0.20712836
RELN 0.20712836
IRF1 0.20712836
CAV1 0.20712836
SOCS7 0.20712836
CAV3 0.20712836
EPS15L1 0.20712836
ATF3 0.20712836
SPIB 0.20712836
PIK3R3 0.20712836
RING1 0.20712836
MATK 0.20712836
TRPV1 0.20712836
KLHL12 0.20712836
KCNB1 0.20712836
NOV 0.20712836
ITGA2B 0.20712836
SMO 0.20712836
PFDN1 0.20712836
MAP3K11 0.20712836
YWHAG 0.20712836
RELA 0.20712836
MYC 0.21550083
STAT1 0.21550083
SRC 0.21983369
ITGA5 0.21983369
CCT5 0.21983369
ANGPT1 0.21983369
GTF2E2 0.22569059
SNX2 0.22569059
TNC 0.22569059
MAGI3 0.22569059
ERH 0.22569059
SH2B3 0.22569059
PFDN6 0.22569059
PLSCR1 0.22595413
PRKCA 0.22595413
NOS3 0.22832049
NR3C1 0.24461159
SHC1 0.24461159
EDN1 0.24462579
MAGI2 0.24462579
CEBPE 0.24462579
PAX5 0.24462579
TRIM23 0.24462579
SYNGAP1 0.24462579
PFDN2 0.24462579
COMMD1 0.24462579
CEP72 0.24730843
CHEK2 0.25130497
EFEMP2 0.25130497
PPP2R1B 0.25130497
SLBP 0.25130497
YWHAZ 0.25218935
BTK 0.25221703
CDKN1B 0.25221703
MAPK1 0.25221703
ERBB3 0.25221703
PAFAH1B3 0.25221703
BDP1 0.25221703
ARF6 0.25221703
PTPN6 0.25221703
STAM2 0.25221703
TGFA 0.25221703
HBEGF 0.25221703
VBP1 0.25221703
CCT8 0.25221703
RFX1 0.25221703
EDF1 0.25221703
DRAP1 0.25221703
PLCG1 0.25980789
RHOA 0.26455324
IL12RB1 0.26455324
IL12B 0.26455324
TP73 0.26455324
IL4R 0.26455324
NEDD8 0.26506766
CUL3 0.26506766
SOCS6 0.26506766
IRS4 0.26506766
SGMS1 0.26506766
GNA11 0.26506766
PFDN4 0.26506766
CBX3 0.26506766
IFNGR1 0.26506766
LEP 0.26506766
DLG4 0.26506766
NTRK1 0.26506766
FLT1 0.26506766
POLR3E 0.26506766
POLR3B 0.26506766
POLR3D 0.26506766
POLR3H 0.26506766
NCK1 0.26506766
TUBA1A 0.26506766
BCL2 0.26506766
TUBG1 0.26506766
DYNLL1 0.27436583
CSNK1D 0.27436583
POLR3A 0.27436583
HSF1 0.27436583
PPIA 0.27436583
CTLA4 0.27436583
UGCG 0.27436583
MDK 0.27436583
EOMES 0.27436583
EEF2K 0.27436583
ITGB3 0.27524446
AKAP9 0.27524446
AKT1 0.27524446
GIT1 0.28187436
CD28 0.28187436
FGFR3 0.28187436
CDK5RAP2 0.28239057
UBB 0.28732216
HRAS 0.28732216
PTN 0.28732216
PTPRA 0.28732216
ELN 0.28732216
PFDN5 0.28732216
DNAJA3 0.28732216
IL27 0.28732216
MLL 0.28732216
LZTS1 0.28908238
PTK2B 0.30282964
NUP153 0.30282964
USP7 0.30282964
NGFR 0.30282964
VAV3 0.30282964
PDCD6IP 0.30282964
EDNRA 0.30282964
PPM1A 0.30282964
CD22 0.30282964
CCT4 0.30282964
IL27RA 0.30282964
TICAM2 0.30282964
SIN3A 0.30492131
EWSR1 0.30492131
RPS6KB1 0.30492131
PRMT1 0.30492131
SMARCA4 0.30492131
POLR3F 0.30492131
NUP214 0.30492131
ABL1 0.30492131
PXN 0.30492131
NFKBIA 0.30492131
EPN1 0.30492131
WRN 0.30492131
EGR1 0.30492131
TOP2A 0.30492131
BMX 0.30492131
ERBB2IP 0.30492131
DAPP1 0.30492131
IRF3 0.30492131
HLA-DRB1 0.30492131
WT1 0.30492131
DAB1 0.30492131
IL2 0.30492131
CEBPB 0.30492131
RBBP7 0.30492131
PPP2CA 0.30492131
CD3E 0.30492131
AZI1 0.30492131
CEP164 0.30492131
CEP290 0.30492131
CEP78 0.30492131
SDCCAG8 0.30492131
TSGA14 0.30492131
CCNA1 0.30492131
GADD45A 0.30492131
PTPRF 0.30492131
WWP2 0.30492131
NID1 0.30492131
F11R 0.30492131
ESR1 0.30492131
NR2F2 0.30492131
GEMIN5 0.30492131
GEMIN6 0.30492131
IL4 0.30492131
CEP135 0.30492131
ODF2 0.30492131
TUBGCP3 0.30492131
CETN2 0.30492131
CEP110 0.30492131
CEP152 0.30492131
CEP192 0.30492131
CEP250 0.30492131
ALMS1 0.30492131
SSNA1 0.30492131
TUBGCP4 0.30492131
TUBGCP5 0.30492131
SFI1 0.30492131
TUBB4 0.30492131
TUBG2 0.30492131
NEDD1 0.30492131
NCOR1 0.30492131
ZBTB17 0.30492131
ATR 0.30492131
ADH4 0.30492131
ADH6 0.30492131
ADH7 0.30492131
NUMB 0.30492131
GTF3C2 0.30492131
PIK3CG 0.30492131
JUND 0.30492131
CDH5 0.30492131
CCT7 0.30492131
CCT3 0.30492131
SPHK1 0.30492131
SNAPC4 0.30492131
SNAPC2 0.30492131
ZNF143 0.30492131
EBI3 0.30492131
ILK 0.30492131
KRT18 0.30492131
ATM 0.30492131
GEMIN7 0.30492131
MMP2 0.30492131
BAD 0.30492131
SMAD3 0.30878515
PCNT 0.30878515
CEP57 0.30878515
CEP63 0.30878515
OFD1 0.30878515
DYNC1I2 0.30878515
DCTN3 0.30878515
MAPK9 0.31260862
SNUPN 0.31260862
PICK1 0.31260862
CCDC90B 0.31305181
STK11 0.31305181
TP53BP2 0.31305181
GHR 0.31305181
TSHR 0.31305181
EFNB2 0.31305181
BRF2 0.31305181
GADD45B 0.31305181
IL18RAP 0.31305181
UBTF 0.31896746
ACTR1A 0.31896746
TUBB2C 0.31896746
DYNC1H1 0.31896746
RASA1 0.31896746
PLK4 0.31896746
PRKAR1A 0.31896746
AP2A2 0.31896746
AGTR1 0.31896746
TFAP2A 0.31896746
ADH1A 0.31896746
ADH1B 0.31896746
ADH1C 0.31896746
HSD11B1 0.31896746
GCKR 0.31896746
PFN1 0.31896746
CTSB 0.31896746
APLP1 0.31896746
RXRG 0.31896746
SAP18 0.31896746
NCOA2 0.31896746
PLK1 0.31896746
PAK1 0.32120273
SMN1 0.32120273
NUP205 0.32120273
AAAS 0.32120273
NUP188 0.32120273
NUP35 0.32120273
NUPL2 0.32120273
PRKACA 0.32120273
JUN 0.32120273
STAT4 0.32120273
IRS2 0.32120273
KRT15 0.32120273
CDC42 0.32120273
MUC1 0.32120273
HSD3B7 0.32120273
NSDHL 0.32120273
SNW1 0.32120273
PHAX 0.32120273
MST1R 0.32120273
TICAM1 0.32120273
PAICS 0.32120273
NFIC 0.32120273
IL18R1 0.32120273
NUP155 0.32120273
NUP93 0.32120273
PRKAR2B 0.32120273
CEP76 0.32120273
SLC9A3R1 0.32662179
IL6ST 0.32662179
KRTAP4-12 0.32826088
NUP88 0.32826088
CENPJ 0.32826088
BCAR1 0.32826088
CHEK1 0.32971153
NPM1 0.32971153
TAF1B 0.32971153
TAF1C 0.32971153
AHR 0.32971153
SH2B2 0.32971153
CD19 0.32971153
NFATC1 0.32971153
MAP2K1 0.32971153
SIN3B 0.32971153
EPOR 0.32971153
RBBP4 0.32971153
NUP210 0.32971153
NFKB1 0.32971153
TYK2 0.33414845
PSMD10 0.33414845
NUP54 0.33414845
RAE1 0.33414845
PCM1 0.33414845
MCM2 0.33414845
GEMIN4 0.33414845
SIP1 0.33414845
MAPK3 0.33414845
TAF1A 0.33414845
HIPK2 0.33414845
SPI1 0.33414845
SUV39H1 0.33414845
GSN 0.33414845
SNAPC5 0.33414845
IL18 0.33414845
APOE 0.33414845
TRIM24 0.33414845
SMAD9 0.33414845
POLA1 0.34171129
CDC25A 0.35058948
RRAS2 0.35058948
HSPG2 0.35058948
UBE3A 0.35275110
MAPK8 0.35338620
CEP70 0.35535253
PIAS1 0.36163141
CD3G 0.36163141
HDAC2 0.36163141
ERBB4 0.36163141
NCL 0.36163141
CCNA2 0.36163141
CEBPA 0.36163141
MAP2K6 0.36163141
EXOSC6 0.36163141
SAP30 0.36869188
INPP5D 0.36869188
GRAP2 0.36869188
CD3D 0.36869188
DDX20 0.36869188
TSG101 0.37007951
TRAM2 0.37007951
ALDH1A1 0.37007951
EPO 0.37007951
BANF1 0.37007951
PLAU 0.37007951
SMPD1 0.37007951
PIAS3 0.37007951
ITGA3 0.37007951
ABCA1 0.37007951
MAGEA11 0.37278775
HGS 0.37278775
BMPR1B 0.37278775
CSNK1E 0.37882736
TUBA4A 0.38104938
CASP7 0.38104938
DOK2 0.38104938
TFDP1 0.38104938
STUB1 0.38104938
CD79B 0.38104938
SUFU 0.38104938
RAF1 0.38705105
TAF9 0.39090243
IL12RB2 0.39090243
RXRA 0.39090243
SFN 0.39090243
EPS15 0.39090243
RAD51 0.39090243
GRIN2D 0.39090243
ATF2 0.39090243
GNAO1 0.39090243
PTPN12 0.39090243
IL6 0.39090243
CREBBP 0.39573538
HD 0.39671633
BRCA1 0.40185035
PLD2 0.40185035
MAP4K1 0.40185035
RBL2 0.40185035
KITLG 0.40185035
RET 0.40185035
SH3GL3 0.40185035
USHBP1 0.40185035
HSPA8 0.40318210
SFRS1 0.40782756
NUP62 0.40881745
CDC2 0.41094557
IL12A 0.41094557
IGF1R 0.41094557
MXD1 0.41094557
CDC7 0.41094557
APEX1 0.41094557
PTMA 0.41094557
NEDD4 0.41094557
GNA13 0.41094557
CSNK2A1 0.41190411
LCK 0.41498126
JAK1 0.41515231
PML 0.41716897
NXF1 0.41716897
VAV1 0.41863752
RANBP2 0.41893001
PRKCD 0.41893001
BCR 0.41893001
RBL1 0.41893001
CASP10 0.41893001
IGHE 0.41893001
DLG3 0.41893001
AR 0.42171480
CSK 0.42171480
NCOA1 0.42171480
EIF2AK2 0.43176650
ZHX1 0.43176650
CD79A 0.43176650
CD4 0.43816988
PTPN1 0.44203082
KPNB1 0.44203082
CDC45L 0.44203082
UTP14A 0.44203082
NCOA6 0.44203082
DLG2 0.44203082
GADD45G 0.44203082
GTF3C1 0.44203082
PAFAH1B1 0.44232451
FASLG 0.44718548
IL2RA 0.44718548
GFI1B 0.44718548
BIRC5 0.44892911
C1orf103 0.44892911
FCER1A 0.45118995
PLCG2 0.45118995
MAP3K1 0.45118995
MYOC 0.45118995
IL2RB 0.45337861
GTF2B 0.45337861
PPP2R1A 0.45367647
AP2A1 0.45986947
AURKA 0.45986947
JUP 0.45986947
KHDRBS1 0.45986947
GNAQ 0.45986947
PRMT5 0.45986947
ACTN2 0.45986947
LYN 0.45986947
GTF2H1 0.46674751
MAPK14 0.46695273
KIAA1377 0.46839141
MMP9 0.47078482
TAF4B 0.47078482
HSPA5 0.47078482
CDK9 0.47646543
JAK3 0.47646543
CTNNB1 0.48047835
KPNA2 0.48047835
KPNA1 0.48047835
MS4A2 0.48047835
GTF2A2 0.48047835
TAF13 0.48047835
NEK2 0.48250948
COPS6 0.49063695
CAMK2A 0.49063695
ADRBK1 0.49063695
FOXA2 0.49063695
TGFB1 0.49063695
PAK2 0.49063695
SFRS7 0.49390649
TUBB 0.49843608
SUMO4 0.49909182
CLASP1 0.49992250
MYOD1 0.50048976
TAF5 0.50048976
GTF2E1 0.50048976
MNAT1 0.50325010
NDE1 0.50429020
CAPN1 0.50844439
UGDH 0.50844439
MBP 0.50844439
FCER1G 0.50844439
TAF6 0.50844439
TAF12 0.50844439
NRIP1 0.50844439
XRCC6 0.51001080
RAN 0.51001080
CASP3 0.51101756
CKAP5 0.51101756
YWHAE 0.51101756
EIF4E 0.51101756
MAPT 0.51621556
GTF2A1 0.51621556
MAPRE1 0.51621556
UBE2I 0.51714460
TRAF2 0.51846274
CD247 0.52432700
EP300 0.52529807
TAF11 0.52581135
FEZ1 0.52581135
GRIN1 0.53851429
TAF10 0.53851429
ZBTB16 0.54135545
NUP85 0.54832966
TAF4 0.55019200
SAT1 0.56164572
COIL 0.56164572
HGF 0.56164572
INS 0.56858109
HDAC1 0.57115802
GNAI2 0.57115802
CDK5 0.57115802
DNM1 0.57115802
SNRPD2 0.57146173
U2AF2 0.57839471
FAS 0.57928297
MAX 0.57928297
CSNK1A1 0.57928297
CSNK2B 0.57928297
IRS1 0.57928297
ARNT 0.57928297
APP 0.58592355
IL2RG 0.58592355
ATN1 0.58592355
POLR2F 0.58592355
CTBP1 0.58592355
DOK1 0.58592355
ARF1 0.59721931
POU2F1 0.59721931
POLR2E 0.60262895
TRAF6 0.60262895
SOCS3 0.60616927
PRKCE 0.60616927
POLR2L 0.60616927
GAB2 0.61569705
PRKCZ 0.61569705
INSR 0.61569705
FN1 0.62266922
NCBP1 0.62266922
ARRB2 0.62266922
HLA-A 0.62266922
VAMP2 0.62266922
BMPR2 0.62266922
LRP1 0.63395543
ERCC3 0.63744194
ACVR1 0.64414455
POLR2H 0.64728697
POLR2K 0.65119223
CPSF2 0.65119223
YWHAB 0.65119223
CREB1 0.65135000
GTF2F2 0.65445552
SFRS11 0.65445552
CPSF3 0.65445552
DHX38 0.65445552
PSMA3 0.65462496
TERT 0.65462496
DAXX 0.65462496
HCK 0.65462496
PSEN1 0.65462496
CDC40 0.65579147
SFRS6 0.65579147
PPP1CC 0.65789448
MAGOH 0.66132701
B2M 0.66132701
RBM8A 0.66737270
PDPK1 0.66963751
POLA2 0.66963751
SFRS5 0.67118385
UPF3B 0.67118385
SFRS9 0.67494300
SRRM1 0.67494300
U2AF1 0.67494300
RBX1 0.67494300
CPSF1 0.68078569
CCNH 0.68078569
SUMO1 0.68094187
NCOR2 0.68094187
IKBKG 0.68094187
SFRS4 0.68391962
ZAP70 0.68951227
CDK7 0.69192823
SFRS3 0.69257987
RNPS1 0.69257987
NUP43 0.69257987
RAC1 0.69257987
RIPK1 0.69412684
NUP133 0.69584148
NUP37 0.69584148
NUP160 0.69584148
ITGAV 0.69945686
HADH 0.69945686
SFRS2 0.69994822
SNRPD1 0.70584680
SMAD4 0.70987053
SNRPF 0.70987053
SYK 0.70987053
GNB2L1 0.71324193
ATXN1 0.72119374
AURKB 0.72236864
SNRPD3 0.72583049
PRPF6 0.74275379
SNRPG 0.74315079
CDC27 0.74331077
TNF 0.74331077
ATP5C1 0.74509565
NHP2L1 0.74509565
NUDT21 0.75124140
CSNK2A2 0.75580136
EIF2S2 0.75580136
NCBP2 0.75930227
RBMX 0.75930227
GSK3B 0.75930227
ZW10 0.75930227
UNC119 0.75930227
SNRPB 0.76097871
YWHAQ 0.76459342
UBE2D1 0.76459342
POLR2I 0.76971386
PSMC3 0.77070006
CCDC85B 0.77242860
PSMB5 0.77415934
CUL1 0.77415934
CDK2 0.77415934
POLR2J 0.77415934
POLR2B 0.77415934
CALM1 0.77742427
POLR2D 0.77742427
SEC13 0.77742427
GTF2F1 0.78102588
RPA1 0.78102588
SETDB1 0.78102588
PSMC2 0.78102588
POLR2G 0.78271420
CDCA8 0.79271239
SKIL 0.79271239
YBX1 0.79385185
RANGAP1 0.80380024
PSMC5 0.80380024
TGFBR1 0.80558042
POLR2C 0.80558042
NDC80 0.80558042
GTF2H4 0.80558042
GTF2H3 0.80558042
DHX9 0.80875770
INCENP 0.80922910
GTF2H2 0.80922910
ERCC2 0.82116652
ACTA1 0.82643141
CASP8 0.83761235
UBQLN4 0.84204146
ATP5D 0.84204146
ATP5E 0.84204146
ATP5F1 0.84204146
ATP5G1 0.84204146
ATP5I 0.84204146
ATP5O 0.84204146
EEF2 0.84354491
RPL11 0.84354491
ATP5H 0.84354491
ATP5L 0.84354491
ATP5J 0.84775637
SMAD2 0.84775637
PSMD11 0.84775637
XPO1 0.84775637
ATP5A1 0.84775637
ACTB 0.84775637
RPL18A 0.84775637
ATP5B 0.84775637
SNRNP70 0.84775637
POLR2A 0.84775637
AASS 0.84775637
SNRPA1 0.84775637
SNRPA 0.84775637
CLP1 0.84775637
CPSF7 0.84775637
CSTF3 0.84775637
DDX23 0.84775637
DNAJC8 0.84775637
HNRNPA0 0.84775637
HNRNPA1 0.84775637
HNRNPA2B1 0.84775637
HNRNPA3 0.84775637
HNRNPD 0.84775637
HNRNPF 0.84775637
HNRNPH1 0.84775637
HNRNPH2 0.84775637
HNRNPL 0.84775637
HNRNPM 0.84775637
HNRNPR 0.84775637
HNRNPU 0.84775637
HNRNPUL1 0.84775637
PCF11 0.84775637
PHF5A 0.84775637
SF3B14 0.84775637
SF3B5 0.84775637
SF4 0.84775637
SNRNP200 0.84775637
SNRNP40 0.84775637
ATP5J2 0.84775637
RBM5 0.84775637
PRPF8 0.84775637
RPL5 0.84775637
SF3A3 0.84775637
SNRPB2 0.84775637
TXNL4A 0.84775637
CSTF1 0.84775637
CCAR1 0.84775637
SF3B2 0.84775637
EFTUD2 0.84775637
PAPOLA 0.84898978
CD2BP2 0.84898978
SF3A2 0.84898978
SF3A1 0.84915488
PRPF4 0.84915488
PABPN1 0.84915488
HNRNPC 0.84915488
SF3B3 0.85215376
PCBP2 0.85506390
SF3B4 0.85788696
SF3B1 0.86062457
PTBP1 0.86584993
VIM 0.86584993
RPS7 0.87075274
SMAD1 0.87075274
CSTF2 0.87633908
LSM2 0.87852436
SMC1A 0.88665154
PCBP1 0.88855545
RPS3A 0.89317054
BUB3 0.91676262
BUB1B 0.92410345
MAD2L1 0.92503688
CDC20 0.92860159
EEF1G 0.92860159
EEF1A1 0.96281629
RPS27 0.97592321
Largest component in the network contains 55 nodes and 135 interactions
Global null model iteration: 1 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 996 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 195 isolated candidate nodes from the input
Final network contains 79 nodes and 72 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 9 nodes and 9 interactions
Global null model iteration: 2 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 811 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 199 isolated candidate nodes from the input
Final network contains 75 nodes and 78 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 11 nodes and 11 interactions
Global null model iteration: 3 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 878 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 200 isolated candidate nodes from the input
Final network contains 74 nodes and 67 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 18 nodes and 26 interactions
Global null model iteration: 4 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 667 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 216 isolated candidate nodes from the input
Final network contains 58 nodes and 42 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 13 nodes and 13 interactions
Global null model iteration: 5 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 545 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 221 isolated candidate nodes from the input
Final network contains 53 nodes and 38 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 11 nodes and 13 interactions
Global null model iteration: 6 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 860 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 212 isolated candidate nodes from the input
Final network contains 62 nodes and 48 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 6 nodes and 7 interactions
Global null model iteration: 7 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 702 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 219 isolated candidate nodes from the input
Final network contains 55 nodes and 44 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 11 nodes and 10 interactions
Global null model iteration: 8 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 819 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 219 isolated candidate nodes from the input
Final network contains 55 nodes and 40 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 8 nodes and 7 interactions
Global null model iteration: 9 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 1056 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 201 isolated candidate nodes from the input
Final network contains 73 nodes and 73 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 44 nodes and 54 interactions
Global null model iteration: 10 / 10
274 / 274 candidate nodes match the name in the network of 9264
nodes
Only test neighbor nodes with local degree equals or exceeds 2
Multiple hypothesis corrections for 622 neighbor nodes in the network
For p-value 0.05 cut-off, 0 nodes were included as linker nodes
Connecting 274 candidate nodes and 0 linker nodes
Remove 220 isolated candidate nodes from the input
Final network contains 54 nodes and 42 interactions
Detecting modules using "edge betweeness" method
Largest component in the network contains 10 nodes and 11 interactions
$globalNull
numOfGenesInput numOfNodes numOfEdges
1 274 9 9
2 274 11 11
3 274 18 26
4 274 13 13
5 274 11 13
6 274 6 7
7 274 11 10
8 274 8 7
9 274 44 54
10 274 10 11
$globalNodesResult
numOfNodes numOfNodesAbove iterations pValueNodes
1 55 0 10 0.09090909
$globalEdgesResult
numOfEdges numOfEdgesAbove iterations pValueEdges
1 135 0 10 0.09090909
###########
Based on 10 random trails
Random networks: mean modularity = 0.304
Random networks: sd modularity = 0.057
Observed network modularity is: 0.519
Observed network modularity z-score is: 3.757
One-tail p-value is: 8.601e-05
null device
1
null device
1 This will be finalized as part of issue #39.
Add
sink()for debugging Galaxy output