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milaboratory / mixcr

MiXCR is an ultimate software platform for analysis of Next-Generation Sequencing (NGS) data for immune profiling.
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For detection of somatic hypermutation (SHM) ? #1648

Closed xmy1990 closed 4 months ago

xmy1990 commented 4 months ago

Hi, Which parameters should I use to detect somatic hypermutation (SHM) in the command "mixcr analyze exome-seq".

or can I use "mixcr analyze exome-seq" to detect somatic hypermutation (SHM).

Thanks

mizraelson commented 4 months ago

Hi, could you specify what type of output you're looking for? By default, MiXCR provides the sequence of all regions that were covered for each clone. If necessary, you can customize the output to include additional columns, such as the number of mutations in a specific region or the mutations themselves.

You can find a complete list of all possible output columns in our documentation.