search

minotm / NTA

Nucleotide augmentation for machine learning-guided protein engineering (https://doi.org/10.1093/bioadv/vbac094, 2022)
MIT License
6 stars 2 forks source link

Does this code have predicted codon sequence output? #1

Closed mintuos closed 1 year ago

mintuos commented 1 year ago

Hello respected author, I tried your code but it did not output the optimized codon or amino acid sequence. Is this normal?

minotm commented 1 year ago

Dear mintuos,

Thanks for your inquiry. The purpose of this repo is data augmentation to improve supervised machine learning workflows for predicting protein function from sequence. The repo does not seek to optimize amino acid or nucleotide sequences. However, a variety of these tools can be found on the web. For example:

https://www.ebi.ac.uk/Tools/st/emboss_backtranseq/ https://www.nature.com/articles/s41598-020-74091-z https://eu.idtdna.com/pages/tools/codon-optimization-tool