EXISTING entry MITE0000075 (fcedc900-a7ee-11ef-9195-02420a630f02)

[mite-bot]

A submission for an existing entry was performed via the MITE Submission portal. Please find the file in the code block below.

Labels

https://github.com/mite-standard/mite_data/labels/review

Review requested

@mmzdouc, @jorgecnavarrom, @adafede

TODO Reviewers

See the (Reviewer Instructions)[https://github.com/mite-standard/mite_data/wiki/How-to-Review-Entries] in the Wiki.

• [x] Automated validation using mite_extras performed
• [x] Factual correctness of submission checked
• [x] Database ID crosslinks verified, added where possible
• [x] References properly formatted
• [x] Automated validation check ID "BBBBBB..." replaced with real reviewer ID

Please propose and discuss changes in the comments.

Proposed changes (compared to current version in mite_data v1.4)

{
    "status": "pending",
    "changelog": {
        "$insert": [
            [
                1,
                {
                    "version": "2",
                    "date": "2024-11-21",
                    "contributors": [
                        "0000-0001-6534-6609"
                    ],
                    "reviewers": [
                        "BBBBBBBBBBBBBBBBBBBBBBBB"
                    ],
                    "comment": "Fixed reaction, replaced wildcards in SMILES with full structures"
                }
            ]
        ]
    },
    "reactions": {
        "0": {
            "reactionSMARTS": "[#6](=[#7]-[#8])-[#6]1:[#6](-[#16]-[#6]):[#6](-[#8]):[#6]:[#6](-[#6]2:[#7]:[#6]:[#6]:[#6]:[#6]:2):[#7]:1>>[#6](=[#7]-[#8])-[#6]1:[#6](-[#16]-[#6]):[#6](-[#8]-[#6]):[#6]:[#6](-[#6]2:[#7]:[#6]:[#6]:[#6]:[#6]:2):[#7]:1",
            "reactions": {
                "0": {
                    "substrate": "CSc1c(O)cc(-c2ccccn2)nc1/C=N/O",
                    "products": [
                        "COc1cc(-c2ccccn2)nc(C=NO)c1SC"
                    ],
                    "description": "O-methylation of collismycin D, resulting in collismycin A"
                }
            },
            "description": "O-methylation of collismycin D, last step of biosynthetic cascape"
        }
    }
}

Submitted Data

{
    "accession": "MITE0000075",
    "status": "pending",
    "changelog": [
        {
            "version": "1",
            "date": "2024-07-30",
            "contributors": [
                "4CEPXXFDQQ46VQJXBT4B4AUO",
                "P75FRHHCFPTCPYSP65VDVPHW"
            ],
            "reviewers": [
                "BBBBBBBBBBBBBBBBBBBBBBBB"
            ],
            "comment": "Initial entry."
        },
        {
            "version": "2",
            "date": "2024-11-21",
            "contributors": [
                "0000-0001-6534-6609"
            ],
            "reviewers": [
                "BBBBBBBBBBBBBBBBBBBBBBBB"
            ],
            "comment": "Fixed reaction, replaced wildcards in SMILES with full structures"
        }
    ],
    "enzyme": {
        "name": "clmM2",
        "description": "O-methyltransferase",
        "references": [
            "doi:10.1016/j.chembiol.2012.01.014"
        ],
        "databaseIds": {
            "uniprot": "H1ZYV4",
            "genpept": "CCC55909.1",
            "mibig": "BGC0000973"
        }
    },
    "reactions": [
        {
            "tailoring": [
                "Methylation"
            ],
            "description": "O-methylation of collismycin D, last step of biosynthetic cascape",
            "reactionSMARTS": "[#6](=[#7]-[#8])-[#6]1:[#6](-[#16]-[#6]):[#6](-[#8]):[#6]:[#6](-[#6]2:[#7]:[#6]:[#6]:[#6]:[#6]:2):[#7]:1>>[#6](=[#7]-[#8])-[#6]1:[#6](-[#16]-[#6]):[#6](-[#8]-[#6]):[#6]:[#6](-[#6]2:[#7]:[#6]:[#6]:[#6]:[#6]:2):[#7]:1",
            "reactions": [
                {
                    "substrate": "CSc1c(O)cc(-c2ccccn2)nc1/C=N/O",
                    "products": [
                        "COc1cc(-c2ccccn2)nc(C=NO)c1SC"
                    ],
                    "isIntermediate": false,
                    "description": "O-methylation of collismycin D, resulting in collismycin A"
                }
            ],
            "evidence": {
                "evidenceCode": [
                    "Inference from genomic data and chemical structure"
                ],
                "references": [
                    "doi:10.1016/j.chembiol.2012.01.014"
                ]
            }
        }
    ]
}

This action was performed by mite-bot

[mmzdouc]

Looks good to me, added to #35