If you switch from a vessel in flight directly to the tracking station via the esc menu, Skopos will lose all connections and stop updating them. Leaving the tracking station will cause skopos to resume correctly tracking connections, and entering the tracking station via the space center screen causes no issues.
Upon further observation, Skopos also seems to rarely drop all connections when going from flight to the space center as well (although it is resolved by a scene change or just waiting?)
If you switch from a vessel in flight directly to the tracking station via the esc menu, Skopos will lose all connections and stop updating them. Leaving the tracking station will cause skopos to resume correctly tracking connections, and entering the tracking station via the space center screen causes no issues.