molgenis / vip

Variant Interpretation Pipeline
https://molgenis.github.io/vip/
GNU Lesser General Public License v3.0
23 stars 5 forks source link

VCF index not created with HTSlib doesn't work #436

Closed dennishendriksen closed 1 year ago

dennishendriksen commented 1 year ago

VCF index created via HTSlib (e.g. BCFtools) adds metadata to the index that is used by bcftools index --stats (context here). This information might not be available when the index is created with other tools, e.g. PyVCF.