Prostaglandin (Medication Used to Lower Intraocular Pressure)

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137760 GLAUCOMA, PRIMARY OPEN ANGLE; POAG

and various types of Glaucoma

Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: a review. JAMA. 2014 May 14;311(18):1901-11. doi: 10.1001/jama.2014.3192. PMID: 24825645; PMCID: PMC4523637.

Prostaglandin analogs (PGAs) are a class of medications used to treat glaucoma, a condition that can damage the optic nerve and lead to vision loss. PGAs work by increasing the outflow of aqueous humor, the fluid that circulates inside the eye, which helps to lower intraocular pressure, a key factor in glaucoma.

PGAs are typically administered as eye drops and are often used as a first-line treatment for glaucoma due to their efficacy and tolerability. Commonly used PGAs include latanoprost, bimatoprost, travoprost, and tafluprost.

PGAs work by increasing the outflow of aqueous humor through the uveoscleral pathway, which is a secondary drainage system in the eye. By increasing the outflow of aqueous humor, PGAs can help to lower intraocular pressure, which can prevent damage to the optic nerve.

PGAs are generally well-tolerated, but they can have side effects such as eye redness, eye irritation, and changes in eye color or eyelash growth. Additionally, PGAs can interact with other medications, so it is important to inform your ophthalmologist of any medications you are currently taking.

PGAs may be used alone or in combination with other medications or treatments, such as beta blockers, alpha agonists, carbonic anhydrase inhibitors, laser trabeculoplasty, and glaucoma surgery.

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There is already an Maxo Term, sorry (MAXO:0000309)