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monarch-initiative / genophenocorr

Genotype Phenotype Correlation
https://monarch-initiative.github.io/genophenocorr/stable
MIT License
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Mtc #160

Closed pnrobinson closed 1 month ago

pnrobinson commented 1 month ago

This PR implements the heuristic method for choosing which terms not to apply tests to. On an example, it skips over 50 terms for correct reasons and this helps with the MTC burden.

pnrobinson commented 1 month ago

@ielis @lnrekerle see this notebook https://github.com/monarch-initiative/genophenocorr/blob/mtc/notebooks/MAPK8IP3/MAPK8IP3.ipynb for an example of the MTC strategy in action -- there is a table showing that we omit over 100 terms prior to testing.

pnrobinson commented 1 month ago

merging to simplify development in next few days.