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monarch-initiative / monarch-disease-ontology-RETIRED

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NCIT_C27474 | Superficial Bladder Carcinoma #366

Closed nicolevasilevsky closed 7 years ago

nicolevasilevsky commented 7 years ago

According to #316, carcinoma != cancer, I believe, so I think this may be incorrect.

NCIT_C27474 Superficial Bladder Carcinoma EquivalentTo DOID_7371 superficial urinary bladder cancer 0.7905298989

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cmungall commented 7 years ago

I'd mark it as correct, carcinoma = cancer and arises-from some epithelial cell.

Although the bladder consists of both epithelium and connective tissue, I believe the 'superficial' here refers to the superficial ureothelium which is epithelial.

Based on both the definition and the superclass in DO, it's a carcinoma:

[Term]
id: DOID:7371
name: superficial urinary bladder cancer
namespace: disease_ontology
def: "A carcinoma of bladder that originates in the epithelial cells (the internal lining) of the bladder wall and is limited to this area." [url:http://www.malecare.com/new_page_91.htm]
synonym: "Superficial urinary bladder carcinoma" EXACT [NCI2004_11_17:C27474]
xref: NCI:C27474
xref: SNOMEDCT_US_2016_03_01:425231005
xref: UMLS_CUI:C1336527
is_a: DOID:4007  ! bladder carcinoma

I think it clearer if DO was to make the primary label ..carcinoma, but what they have is not internally inconsistent (note I can't speak to how cancer clinicians use this term)

Note the NCIT def is:

"A term used by urologists to describe an infiltrating carcinoma of the bladder that has not invaded into the muscularis propria of the bladder wall regardless of histologic type or grade."

nicolevasilevsky commented 7 years ago

Sounds good, I think we can close this ticket then.