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monarch-initiative / mondo

Mondo Disease Ontology
http://obofoundry.org/ontology/mondo
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[NTR] Kawasaki-like syndrome #1837

Closed nicolevasilevsky closed 4 years ago

nicolevasilevsky commented 4 years ago

Preferred term label: Kawasaki-like syndrome

Definition (free text, please give PubMed ID, if applicable, in format PMID:#######) see: https://medicalxpress.com/news/2020-06-kawasaki-like-syndrome-linked-covid-children.html

Parent term (use OLS, or your favorite ontology browser) COVID-19

cc @pnrobinson

pnrobinson commented 4 years ago

Prefered label: SARS-CoV-2 Kawasaki-like syndrome

Syn COVID-19 Kawasaki-like syndrome Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 Paediatric Inflammatory Multisystem Syndrome: Temporally Associated with SARS-CoV-2 Synonym (abbreviation): PIMS-TS

Def: A inflammatory syndrome in children infected by the SARS-CoV-2 with similarities to Kawasaki disease. Clinical manifestations range from fever and inflammation to myocardial injury, shock, and development of coronary artery aneurysms. PMID:32511692 PMID:32529358 PMID:32630212

Comment: The clinical presentation of MIS-C includes fever, severe illness, and the involvement of two or more organ systems, in combination with laboratory evidence of inflammation and laboratory or epidemiologic evidence of SARS-CoV-2 infection. Some features of MIS-C resemble Kawasaki Disease, toxic shock syndrome, and secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome.