monarch-initiative / mondo

Mondo Disease Ontology
http://obofoundry.org/ontology/mondo
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[Revise subclass] Malaria; Melanoma #6369

Closed katiermullen closed 1 year ago

katiermullen commented 1 year ago

Mondo term (ID and Label) MONDO:0005105 Melanoma MONDO:0005136 Malaria

Suggested revision and reasons While working on the non-human animal branch, it was noted that melanoma is an inferred subclass of 'endocrine system' and 'endocrine gland' and I am not sure if that relationship is correct.

Malaria is an inferred subclass of 'alimentary part of gastrointestinal system' and I am not sure if this relationship is correct.

Your nano-attribution (ORCID) https://orcid.org/0000-0002-5002-8648

nicolevasilevsky commented 1 year ago

@katiermullen

Malaria is an inferred subclass of 'alimentary part of gastrointestinal system' and I am not sure if this relationship is correct.

I believe this is because of the subclass Of axiom: 'disease has location' some hepatocyte

which seems accurate according to this paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783171/

We can remove this axiom if it is causing issues. When you run the reasoner, can you quick the question mark to explain the inference, and we can confirm this is correct?

image
nicolevasilevsky commented 1 year ago

re: melanonma, I excluded the parent 'neuroendocrine neoplasm'

nicolevasilevsky commented 1 year ago

discussed on curation call, we should remove the subclass assertion related to liver above