Pubmed and other related databases return scant, if any, dedicated medical definitions of Dysostosis. When Dysostosis is mentioned in the literature, it is typically in relation to specific disease etiologies like Cleidrocranial Dysostosis (PMID:34367447 , source: https://pubmed.ncbi.nlm.nih.gov/34367447/), Spondylocostal Dysostosis (PMID: 8200707, source: https://pubmed.ncbi.nlm.nih.gov/8200707/), and Mandibulofacial Dysostosis (PMID:32965901, source: https://www.ncbi.nlm.nih.gov/books/NBK562230/). Furthermore, the use of Dysostosis in clinical medicine is questionable.
Scant clinical usage along with its broad categorization necessitates re-examining Dysostosis as a parent class, or obsoleting the term.
Dysostosis Definition: Dysostosis multiplex is a term that refers to the multiple abnormalities that are seen on radiographs of bones. (Source: https://www.sciencedirect.com/topics/veterinary-science-and-veterinary-medicine/dysostosis#:~:text=Dysostosis%20multiplex%20is%20a%20term,seen%20on%20radiographs%20of%20bones.)
Pubmed and other related databases return scant, if any, dedicated medical definitions of Dysostosis. When Dysostosis is mentioned in the literature, it is typically in relation to specific disease etiologies like Cleidrocranial Dysostosis (PMID:34367447 , source: https://pubmed.ncbi.nlm.nih.gov/34367447/), Spondylocostal Dysostosis (PMID: 8200707, source: https://pubmed.ncbi.nlm.nih.gov/8200707/), and Mandibulofacial Dysostosis (PMID:32965901, source: https://www.ncbi.nlm.nih.gov/books/NBK562230/). Furthermore, the use of Dysostosis in clinical medicine is questionable.
Scant clinical usage along with its broad categorization necessitates re-examining Dysostosis as a parent class, or obsoleting the term.