morispi / CONSENT

Scalable long read self-correction and assembly polishing with multiple sequence alignment
https://doi.org/10.1038/s41598-020-80757-5
GNU Affero General Public License v3.0
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CONSENT on clustered cDNA with small Window Size #30

Closed jkbenotmane closed 3 years ago

jkbenotmane commented 3 years ago

Hi after reconsidering CONSENT-correct,

wouldn´t it make sense to use it with a small clustered Reads from a Clustering Algorithm (e.g. isONClust, RATTLE) and then correct the Reads using a small Windowsize to retain highly variable Splice Junctions?

Trying that approch gave me considerable Results but I couldn´t lower the window Size lower then 70. Might this be related to Computation Power (I am trying it on Laptop with 64Gb Ram) or might there be a deeper Reason?