morris-lab / Capybara

Capybara: A computational tool to measure cell identity and fate transitions
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a question of QP #16

Open lengfei5 opened 2 years ago

lengfei5 commented 2 years ago

Dear Capybara team,

Thanks for developing this QP extension for transition cell type annotation. I just have a basic question regarding QP when I read your paper. In the identify score vector f_t, there are two constrains, 1) f_t between 0 and 1 2) sum of f_t <=1

I tend to interpret the f_t here as identify fraction (0% - 100%) of each cell identifies in the reference. It is natural that the sum is equal to 1 or 100%. But I get a bit confused by the < 1, meaning there are some cell identities missing in the reference ? Thank you.