morris-lab / CellOracle

This is the alpha version of the CellOracle package
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motif_analysis.scan runtime crash: Segmentation fault: 11 #33

Closed gav-sturm closed 3 years ago

gav-sturm commented 3 years ago

While running tfi.scan I am running into the following error which seems to be related to (https://kb.iu.edu/d/aqsj). Any ideas what could be causing this? I am using human, hg38, reference genome and using 14000 peaks from ATACseq data. I have run it with the default motifs and the program still crashes.

Here is the output: Checking your motifs... Motifs format looks good.

Initiating scanner...

Calculating FPR-based threshold. This step may take substantial time when you load a new ref-genome. It will be done quicker on the second time.

Convert peak info into DNA sequences ...

Scanning motifs ... It may take several hours if you proccess many peaks.

HBox(children=(HTML(value=''), FloatProgress(value=1.0, bar_style='info', layout=Layout(width='20px'), max=1.0), HTML(value=''))) Segmentation fault: 11

KenjiKamimoto-ac commented 3 years ago

HI gav-strum,

It seems that gimmemotifs crushed during the scanning process. gimmemotifs is one of the python package used in the celloracle. As you suspected, I think "Segmentation fault: 11" is a basic memory error. However I cannot identify the cause of this problem. The possible reasons are below.

If possible, can you please try to use celloracle in a different PC? I guess a computer with larger memory will help.