morrislab / phylowgs

Application for inferring subclonal composition and evolution from whole-genome sequencing data.
GNU General Public License v3.0
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LLH always equal to -Inf #129

Open DavideMaspero opened 4 years ago

DavideMaspero commented 4 years ago

Hi,

I'm trying to use your tool to analyze longitudinal ssm data, the problem is that phyloWGS computes a likelihood equal to -inf for each sampled tree. This is the first line of the ssm_data file (I also pass an empty cnv_data file): id gene a d mu_r mu_v s0 BIRC3_102195674_A 10807,6335,1765,4096,5609,3952,6872,7831,6755,5673,5376,5609 3,0,9,1,2,2,0,14,1,0,3,2 0.9 0.4

Am I doing something wrong? Do you have any suggestion to solve the issue?

Thank you in advance, Best regards,

Davide Maspero