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mpallocc / auto-go

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Selection of background/universe #16

Open josruirod opened 4 months ago

josruirod commented 4 months ago

Hi and thanks for the work, autoGO is a very convenient package that we use a lot.

I want to ask regarding the universe/background that is used in the statistical tests of these analyses. It's the total number of genes in each particular library used, right? Is there any way of customizing that parameter with another gene list. This is a crucial parameter in many studies.

Apparently, this became possible in enrichr (issue) so it seems that a parameter could be added in a new version of autoGO?

Thanks for the support

isabellagrassucci commented 3 months ago

Hi @josruirod , thanks for the question.

The background list is not customizable yet but it is a parameter we want to add for sure in a new version of AutoGO. This is because the package employs the original Enrichr API which is cleaner and easier when building the package. Thanks again,

Isabella