Can this algorithm be employed to other targeted sequencing data?

mskcc / DeepSig

Single-Base Substitution Mutational Signature Inference for WES and MSK-IMPACT

MIT License

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Can this algorithm be employed to other targeted sequencing data? #3

Closed lincj1994 closed 9 hours ago

lincj1994 commented 10 hours ago

Hi.

I'm wondering if this algorithm can be employed to targeted sequencing panel other than MSK-IMPACT?

Thanks.

junwoo2 commented 9 hours ago

Panel dependence would come mostly from mutation count distribution, regarding how different it is from WGS. It is expected to be applicable if the panel size is similar.