CF and subclonality? - Githubissues

mskcc / facets

Algorithm to implement Fraction and Copy number Estimate from Tumor/normal Sequencing.

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CF and subclonality? #134

Open jh2663 opened 5 years ago

jh2663 commented 5 years ago

Hi. I just want to get subclonal SCNAs vs clonal SCNAs from FACETS output file. Is it right to look up the cellular fraction (CF) value to judge which ones are clonal or subclonal? If so, close to 1 of CF (not 1) should be clonal but what would be the reasonable cutoff to say subclonal?

Please correct me if I am wrong at some points. thanks.

edceeyuchen commented 1 year ago

@jh2663 Hello！I have the same problem, and now, could you give me some advise? Thank you very much~