mskcc / facets

Algorithm to implement Fraction and Copy number Estimate from Tumor/normal Sequencing.
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Purity NA - (with observed CN changes!) #171

Open alexcoulton opened 2 years ago

alexcoulton commented 2 years ago

Hello,

In the following issues, where users have derived NA purity values, the response has been that this is due to a lack of copy number changes:

https://github.com/mskcc/facets/issues/66 https://github.com/mskcc/facets/issues/68

I however get an NA purity value even though there is a clear copy number change on chromosome 3 when using FACETs:

image

Why is the purity NA in this case?