mskcc / facets

Algorithm to implement Fraction and Copy number Estimate from Tumor/normal Sequencing.
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cf.em too low? #198

Open THT-sleepy opened 2 months ago

THT-sleepy commented 2 months ago

Hello there As far as I know most cnv should be clonal, however most of my results have cnv with a low cf.em. How should I know if it's wrong because of incorrect cval I set(150) or incorrect purity/ploidy estimation(I think it's equal to estimation of dipLogR) . Below is an example: Tumor1-AD1.pdf Thank you in advance. Best Huatao