conversion g. to c. issue

[vasvale]

NC_000011.9:g.47364696_47364697insACC becomes NC_000011.9(NM_000256.3):c.1227_1228insGTG

is this correct? should it be ins GGT?

[jfjlaros]

The transcript in question resides on the reverse complement strand, so the 3' rule is applied in the opposite direction of that of the genome, hence the rotation.