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nanoporetech / dorado

Oxford Nanopore's Basecaller
https://nanoporetech.com/
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dorado RNA m6A basecall model #944

Closed yinyuanmtu closed 2 months ago

yinyuanmtu commented 3 months ago

Dear developers, I am wondering whether the dorado RNA base call models (both the m6A DRACH motif model and all-context model) will work for rRNA and organellar RNAs. I have seen pretty good m6A base calling for poly(A) mRNA, but a lot of failed base calling for chloroplast RNAs, mitochondria RNAs and rRNAs. Note these different types of RNA that I mentioned are derived from same RNA 004 dataset. I would greatly appreciate your thoughts on this matter. Many thanks!

HalfPhoton commented 3 months ago

Hi @yinyuanmtu, this type question is probably best placed on the Nanopore Community.