naobservatory / mgs-pipeline

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alignments: additionally align against human genome #50

Closed jeffkaufman closed 7 months ago

jeffkaufman commented 7 months ago

We'd like to treat reads that come from the human genome differently. Use the mdethod described at https://www.metagenomics.wiki/tools/short-read/remove-host-sequences to identify human reads.

This uses the standard Bowtie human genome DB, and splits the alignments pipeline stage into one round with the human DB and another with the custom HV DB.