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naobservatory / p2ra

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Simon aav update #170

Closed simonleandergrimm closed 1 year ago

simonleandergrimm commented 1 year ago

Adds AAV5 and AAV6, and updated seroprevalence of AAV2 to represent a the unweighted global seroprevalence average.

@jeffkaufman Let me know if one PR for AAV 5 and 6 is fine or if I should have separated these.

jeffkaufman commented 1 year ago

Since this source also has AAV8 and AAVrh10, why not include them too?

Turns out virus-host DB doesn't think AAV8 is human-infecting: https://www.genome.jp/virushostdb/view/?search_text=202813

And the NCBI taxid doesn't seem to include rh10: https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Undef&id=10803&lvl=3&keep=1&srchmode=1&unlock

So probably adding 5 and 6 is good enough!

simonleandergrimm commented 1 year ago

@jeffkaufman Flagging that this is still open.