naobservatory / p2ra

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Added JC Virus, BK Virus, and MC Virus estimates for Denmark, fixed US prevalence for MCV #204

Closed simonleandergrimm closed 1 year ago

simonleandergrimm commented 1 year ago

This PR does two things:

  1. Create Danish AAV estimates

As noted in the scripts, I used a Dutch study (Table 2) to estimate MC Virus prevalence but didn't use this same study for JC and BK Virus, as the immunoassay, described in a different paper by the same author, showed cross-reactivity for JC and BK Virus. (link). This could also explain why the measurement for BK Virus is suspiciously high (98.9%).

Instead of the Dutch study, I used the Swiss study to extrapolate JC and BK Virus to Denmark.

  1. MCV prevalence typo Fixed a typo that led to a 100x too large prevalence for MCV. ( 59.4 * 100_000 -> 0.594 * 100_000). I failed to spot this previously, but this explains why the expected relative abundance for MCV is so low!
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