Can we use non sequencing based inputs?

natsuhiko / rasqual

Robust Allele Specific Quantification and quality controL

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Can we use non sequencing based inputs? #20

Open bioinfograd opened 5 years ago

bioinfograd commented 5 years ago

This may be a dumb question but I have RT-PCR expression data or methyl array data for a set of genes that I would like to look at, could I just supplement this for “counts”? Or is there another tool to look at QTLs based on these inputs?

natsuhiko commented 5 years ago

Hi,

I don't think it is a good idea to fit discrete distributions on continuous data. I would go for linear regressions to see QTL signals.

Best regards, Natsuhiko