navinlabcode / copykat

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macrophages with CNV? #107

Open sadiexiaoyu opened 7 months ago

sadiexiaoyu commented 7 months ago

Hi, I am using copykat to calculate CNV on a cancer sample, and results showed that not only cancer cells, but also there were a lot of macrophages with CNV. Could macrophages have CNV in cancer sample?

23ycjiang commented 2 weeks ago

Hello,sadiexiaoyu I have some questions about the DCIS1 dataset and I really need your help. In copyKAT, only the data of RNA-SEQ are provided for CNV detection. Then the bulk DNA sequencing and whole-exome sequencing analysis methods served as ground truth when carrying out the index middle distance calculation of this method Where can I download reference? I only found the same scRNA data in the copykat paper mentioned in the article. Looking forward to your reply very much. Thank you very, very much. Your reply is important to me.