How to deal with multiple libraries?

ndierckx / NOVOPlasty

NOVOPlasty - The organelle assembler and heteroplasmy caller

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How to deal with multiple libraries? #113

Closed LIZW2019 closed 4 years ago

LIZW2019 commented 5 years ago

Hi,

Great appreciation for your wonderful job! I am now working on a soybean genome, its raw sequencing data are made up of two libraries, both contain all the information in soybean genome, just with different insert lengths(270bp VS 500bp). Which one should I choose? Or should I do them both and choose the better result? Or try to merge them together first? Looking forward to your answer!

God bless you, Li

ndierckx commented 4 years ago

Hi,

Currently it is not possible to combine multiple libraries. I would try both, because assemblies don't take long. If you don't have enough coverage, you could just merge both and give an insert size in the middle.