neksa / mutagene

Python library and package for mutational analysis
https://www.ncbi.nlm.nih.gov/projects/mutagene/
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arguments in motif search #32

Closed anna-panchenko closed 4 years ago

anna-panchenko commented 4 years ago

Currently thresholds "-t" are not included in "advanced arguments". We should also include thresholds on individual p-values.

I don’t think it is clear what “TN”, “NA”… mean; I would call these options “transcribed”,”non-transcribed”, “any” or “both” (“TN”?)

--save-motif-matches “save mutations in matching motifs to a BED file”

neksa commented 4 years ago

I can see -t in advanced arguments (version 0.9.0):

--threshold THRESHOLD, -t THRESHOLD Significance threshold for qvalues, default value=0.05

TN is essentially two consecutive, independent tests: first T, then N. A means we consider all mutations in one test. I will simplify the help usage message. It's either T or N or A

Changed --save-motif-matches help