nerettilab / RepEnrich2

RepEnrich2 is an updated method to estimate repetitive element enrichment using high-throughput sequencing data.
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Use in ChIP Seq Analysis #31

Open jesswhitts opened 8 months ago

jesswhitts commented 8 months ago

Hello,

I was just wondering what you would recommend when trying to integrate peak calling pipelines with RepEnrich. We want to generate a set of ChIP peaks which we can identify as overlapping with TE regions or not.

Should we call peaks on the full bam file (uniquely mapped and multimapped reads), or just the uniquely mapped ones?

Many thanks, Jess