I am trying to understand why I cannot properly generate a quantile ( numberOfBins=4) from the Zeisel data accessible through EWCE pkg
To make sure I am understanding properly. Is it that there is not enough gene expression difference in the Zeisel dataset to generate
quantiles based on higher to lower % of genes expressed?
I would appreciate some help understanding what is going on in the Zeisel data.
Console output
Standardising CellTypeDataset
Found 3 matrix types across 5 CTD levels.
Processing level: 1
Converting to sparse matrix.
Processing level: 2
Converting to sparse matrix.
Processing level: 3
Converting to sparse matrix.
Processing level: 4
Converting to sparse matrix.
Processing level: 5
Converting to sparse matrix.
Converting to sparse matrix.
Converting to sparse matrix.
Converting to sparse matrix.
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
Converting to sparse matrix.
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
+ <2 non-zero quantile bins detected in column. Assigning these values to default quantile ( 5 )
Converting to sparse matrix.
Checking CTD: level 1
WARNING: 4 columns (cell-types) have less than the expected number of quantile bins (4).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 2
WARNING: 3 columns (cell-types) have less than the expected number of quantile bins (4).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 3
WARNING: 6 columns (cell-types) have less than the expected number of quantile bins (4).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 4
WARNING: 26 columns (cell-types) have less than the expected number of quantile bins (4).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 5
WARNING: 205 columns (cell-types) have less than the expected number of quantile bins (4).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 1
WARNING: 1 columns (cell-types) have less than the expected number of quantile bins (10).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 2
WARNING: 1 columns (cell-types) have less than the expected number of quantile bins (10).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 3
WARNING: 6 columns (cell-types) have less than the expected number of quantile bins (10).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 4
WARNING: 30 columns (cell-types) have less than the expected number of quantile bins (10).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
Checking CTD: level 5
WARNING: 228 columns (cell-types) have less than the expected number of quantile bins (10).
This may be due to an excessive sparsity or insufficient variation in your CellTypeDataset.
The CTD is already converted to human orthologs, so set the input species to "human. or leave the default, and it will automatically infer the correct species.
1. Bug description
I am trying to understand why I cannot properly generate a quantile ( numberOfBins=4) from the Zeisel data accessible through EWCE pkg
To make sure I am understanding properly. Is it that there is not enough gene expression difference in the Zeisel dataset to generate quantiles based on higher to lower % of genes expressed?
I would appreciate some help understanding what is going on in the Zeisel data.
Console output
2. Reproducible example
Code
3. Session info